Results 61 to 70 of about 468,339 (258)

Imaging the Three-Dimensional Ionospheric Structure with a Blob Basis Functional Ionospheric Tomography Model

open access: yesSensors, 2020
A new ionospheric tomography model is presented in this work. In the new model, the traditional voxel basis function is replaced by the blob basis function.
Debao Wen, Dengkui Mei, Yanan Du
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Long Term Global Ionospheric Total Electron Content Trend Analysis

open access: yesGeophysical Research Letters
Simulations based on physical models of the thermosphere‐ionosphere system suggest that the ionosphere will sink as the thermosphere cools and contracts in response to increasing greenhouse gas concentrations.
M. Paula Natali   +6 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

ANALISA PERUBAHAN IONOSFER AKIBAT GEMPA MENTAWAI TAHUN 2010 (Studi Kasus : Kepulauan Mentawai, Sumatra Barat)

open access: yesJurnal Teknik ITS, 2017
Gempa merupakan fenomena alam akibat aktifitas tektonik yang sering terjadi di Indonesia. Sepanjang pulau Sumatra merupakan pertumbukan antara lempeng Indo-Australia dan lempeng Eurasia menjadikan Sumatra sebagai daerah paling aktif dengan aktifitas ...
Leni Septiningrum
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Total electron content variations in the ionosphere before the Colima, Mexico, earthquake of 21 January 2003 [PDF]

open access: yesGeofísica Internacional, 2005
Anomalous ionospheric variations associated with the process of strong earthquake (M>5) preparation has been fairly well established. To check possible ionospheric variations connected with the recent Colima earthquake, M=7.8, of 21 January 2003, the ...
G. Bisiacchi-Giraldi   +3 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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