Results 71 to 80 of about 1,151,732 (292)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Study of the TEC data obtained from the DORIS stations in relation to seismic activity

open access: yesAnnals of Geophysics, 2007
Ionospheric data obtained from the DORIS system are used in this paper. The DORIS system is composed of several ground-based beacons which emit at two frequencies (400 MHz and 2 GHz) and of receivers on board several satellites (currently SPOT2,
M. Parrot, F. Li
doaj   +1 more source

Ionospheric effects of the solar flares of September 23, 1998 and July 29, 1999 as deduced from global GPS network data [PDF]

open access: yes, 2000
This paper presents data from first GPS measurements of global response of the ionosphere to solar flares of September 23, 1998 and July 29, 1999. The analysis used novel technology of a global detection of ionospheric effects from solar flares (GLOBDET)
A.T. Altyntsev   +27 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Imaging the Three-Dimensional Ionospheric Structure with a Blob Basis Functional Ionospheric Tomography Model

open access: yesSensors, 2020
A new ionospheric tomography model is presented in this work. In the new model, the traditional voxel basis function is replaced by the blob basis function.
Debao Wen, Dengkui Mei, Yanan Du
doaj   +1 more source

Transport, magnetic, and structural properties of La$_{0.7}$Ce$_{0.3}$MnO$_3$ thin films. Evidence for hole-doping

open access: yes, 2008
Cerium-doped manganite thin films were grown epitaxially by pulsed laser deposition at $720 ^\circ$C and oxygen pressure $p_{O_2}=1-25 $Pa and were subjected to different annealing steps. According to x-ray diffraction (XRD) data, the formation of CeO$_2$
Bals, S.   +8 more
core   +1 more source

Regional reference total electron content model over Japan based on neural network mapping techniques [PDF]

open access: yes, 2007
A regional reference model of total electron content (TEC) was constructed using data from the GPS Earth Observation Network (GEONET), which consists of more than 1000 Global Positioning System (GPS) satellite receivers distributed over Japan.
T. Maruyama
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Development of Ionospheric Tomography Model Using GPS [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2006
We produced the electron density distribution in the ionosphere over South Korea using the data from nine permanent GPS (Global Positioning System) stations which have been operated by KASI (Korea Astronomy and Space Science Institute).
Byung-Kyu Choi   +2 more
doaj   +1 more source

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