Results 241 to 250 of about 72,933 (307)

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Beyond the host: Unveiling the independent microbiome of equine gastrointestinal nematodes. [PDF]

PLoS One
Gentilini F, Ogundipe TG, Turba ME, Romagnoli N, Lambertini C, Pollera C, Cremonesi P, Stancampiano L.   +7 more
europepmc   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

Drug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz, Linus Korsmeier, Andreas Thomas, Mario Thevis   +3 more
wiley   +1 more source

Gastrointestinal parasites in West African chimpanzees (Pan troglodytes verus) in Fongoli (Kedougou, Senegal). [PDF]

Primate Biol
Sy PM, N'da KM, Ndiaye PI, Gbati OB, Pruetz JD.   +4 more
europepmc   +1 more source

Hot spots or hot moments? Contextualizing the spatio‐temporal scale of research on animal inputs

Ecography, EarlyView.
Mammals play important roles in redistributing elements across ecosystems, concentrating biogeochemical inputs across both space and time. However, research on zoogeochemical inputs is often constrained by logistical considerations, potentially limiting our knowledge of mammals' impacts on biogeochemical patterns and processes.
Kristy M. Ferraro, Elizabeth S. Forbes, Andrew J. Abraham, Julia D. Monk   +3 more
wiley   +1 more source

Prevalence, quantification, and household-level risk factors associated with Salmonella spp. infection in chickens in Boussouma commune, Burkina Faso. [PDF]

BMC Microbiol
Tiendrébéogo WPB, Kagambèga A, Moodley A, Ochieng L, Da TA, Tao R, Ilboudo AK, Ouedraogo B, Ilboudo G, Barro N, Dione M.   +10 more
europepmc   +1 more source

Over three‐quarters of earthworm species lack protection in China, a crisis exacerbated by climate change

Ecography, EarlyView.
Earthworms, as ‘ecosystem engineers', play a crucial role in regulating ecosystem functions and shaping community structures. Due to climate change, earthworms face severe survival pressures and extinction risks. However, whether conservation efforts targeting aboveground biodiversity can cover the long‐neglected earthworm diversity remains unknown. To
Yajie Zhou, Shuo Zhang, Wen Qin, Zhuoyi Wu, , Shaolin Peng, Ting Zhou   +6 more
wiley   +1 more source

Clinical cases of <i>Cryptosporidium</i> spp. infections in parrots, canaries and pigeons confirmed by molecular and immunochromatographic methods. [PDF]

J Vet Res
Jańczak D, Maj AK, Górecki P, Szaluś-Jordanow O, Golke A.   +4 more
europepmc   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source