Results 191 to 200 of about 195,942 (257)

Protocol of the LEONORA randomized clinical trial: Lower gastrointestinal symptom burden by prophylaxis with synbiotics after colorectal cancer surgery. [PDF]

BMC Cancer
Schöttker B, Kopp-Schneider A, Biehl L.
europepmc   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Impact of Diet and Drugs on Fecal Lachnoclostridium Gene Marker (m3) in Non-Invasive Diagnosis of Colorectal Neoplasia. [PDF]

J Gastroenterol Hepatol
Dai M, Lau LHS, Shi H, Sun Y, Li X, Li M, Wang H, Lau RI, Liang JQY, Chan FKL, Ng SC.   +10 more
europepmc   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

The Centers for Medicare and Medicaid Services and others misunderstand stool testing for colorectal cancer. [PDF]

J Natl Cancer Inst
Coronado GD, Hoffman RM, Llavona-Ortiz J, Rutter CM.   +3 more
europepmc   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

BMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu, Baoqin Song, Zhihao Chen, Wenzhong Li, Wanjun Liang, Xiu Wang   +5 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Viable gut bacterial metrics associated with intestinal eubiosis and dysbiosis. [PDF]

Gut Microbes Rep
Naito T, Setoyama H, Kato-Nagaoka N, Shima T, Sato T, Moriyama-Ohara K, Arase S, Kurakawa T, Horino-Higuchi M, Tajima S, Suzuki-Ohnari T, Aiyama-Suzuki Y, Hara T, Naito E, Hayashi N, Tsuruta K, Hori T, Kataoka-Kato A, Fukuda R, Mitsuyama K, Matsumoto S, Tsuji H.   +21 more
europepmc   +1 more source

Ecology and evolution of pyrazines in insects

Biological Reviews, EarlyView.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk, Niklas Wahlberg, Johanna Mappes   +2 more
wiley   +1 more source

Fecal carriage of carbapenemase-producing Escherichia coli and Klebsiella spp. and associated factors among dairy farm milkers in Tigray Region, Northern Ethiopia. [PDF]

BMC Microbiol
Gebru GG, Muthupandian S, Kassaye E.
europepmc   +1 more source