Results 101 to 110 of about 13,562,066 (260)

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Tracey Moffatt Collection

open access: yes
Tracey Moffatt is a photographer and director. This collection focuses on her film career, including the films Nice Coloured Girls (1987), Night Cries: A Rural Tragedy (1990) and BeDevil (1993).

core  

New Jersey Neighborhoods Collection

open access: yes, 2007
This collection captures the essence of New Jersey's thriving and ever-changing ...

core   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian   +10 more
wiley   +1 more source

Total Eclipse: Lee Lozano's Energy Paintings [PDF]

open access: yes
Through a discussion of the concept of roundness in the artist's thinking, this essay examines the origins of Lee Lozano's Wave paintings.
Vilalta, Helena
core   +2 more sources

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

open access: yesAdvanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen   +13 more
wiley   +1 more source

Westerns Genre Collection

open access: yes
This is a collection of materials at the AFI Research Collection (AFIRC) that relate to the genre of film commonly known as Westerns. Westerns were once a popular staple of films produced by the USA, whose influence was felt in many other countries (for ...

core  

Gunn Collection

open access: yes, 2016
Professor Emeritus Drewey Wayne Gunn served as an active Texas A&M University-Kingsville University faculty member from 1968 to the present (except for a sojourn in Denmark as a Fulbright teacher and in France as an ESL teacher from 1972 to 1977). He is
Drewey Wayne Gunn Collection
core  

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

open access: yesAdvanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han   +10 more
wiley   +1 more source

27a.34c Unloading simulated feces

open access: yes
This image reflects a view of Unloading simulated feces from a Waste Collection ...

core   +1 more source

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