Results 181 to 190 of about 86,076 (224)

Development of a sustainable water treatment process using biochar as substrate for filtration and coliform removal

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Preparation, modification, and characterization of biochar from woodchips and its application in stream water filtration, evaluated through physicochemical and microbiological analyses. Abstract Global microbial water contamination affects 1.8 billion people, necessitating efficient and sustainable treatment methods.
Tariq Khalil   +8 more
wiley   +1 more source

Clinical Characterization of Enzyme and Transporter Precipitants to Evaluate Drug–Drug Interactions for Orforglipron, a Small Molecule Glucagon‐Like Peptide‐1 Receptor Agonist

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Orforglipron is an orally administered, small‐molecule glucagon‐like peptide‐1 receptor agonist in clinical development for the treatment of type 2 diabetes and obesity. Orforglipron is a substrate of CYP3A4, organic anion transporting polypeptides (OATPs) 1B/1B3, and P‐glycoprotein (P‐gp); however, precipitants commonly used to define these mechanisms
Bridget L. Morse   +7 more
wiley   +1 more source

Ecopipam, a Dopamine D1 Receptor Antagonist: Pharmacokinetics, Mass Balance, and Metabolism in Healthy Volunteers. [PDF]

open access: yesClin Transl Sci
Schmith VD   +7 more
europepmc   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó   +7 more
wiley   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang   +4 more
wiley   +1 more source

Draft genome sequence of <i>Enterococcus raffinosus</i> strain MEBT1 isolated from the feces of children with diarrhea. [PDF]

open access: yesMicrobiol Resour Announc
Antor MA   +8 more
europepmc   +1 more source

Novel Noninvasive Broad‐Spectrum Infrared Treatment of Ulcerative Colitis by Modulating T‐Cell Relocation

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A novel graphene‐based broad‐spectrum infrared (BSIR) device is developed for the noninvasive treatment of ulcerative colitis (UC). BSIR irradiation effectively alleviates colonic inflammation and accelerates mucosal recovery by inducing the systemic relocation of T lymphocytes to the spleen.
Siyu Chen   +15 more
wiley   +1 more source

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