Results 81 to 90 of about 8,236,191 (249)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Distributed Graph Simulation: Impossibility and Possibility [PDF]
, 2014 This paper studies fundamental problems for distributed graph simulation. Given a pattern query Q and a graph G that is fragmented and distributed, a graph simulation algorithm A is to compute the matches Q(G) of Q in G.
Wang, Xin +3 more
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Analysis of Z64 genetic code network [PDF]
Network BiologyThe genetic code is the set of rules defining how the sequence of nucleotides in DNA or RNA determines the specific amino acid sequence in the synthesis of protein.
Adil Akhtar, Nasrin Irshad Hussain
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Complement of the generalized total graph of fields
AKCE International Journal of Graphs and Combinatorics, 2020 Let R be a commutative ring and H be a multiplicative prime subset of R. The generalized total graph is the undirected simple graph with vertex set R and two distinct vertices x and y are adjacent if For a field F, is the only multiplicative prime subset
T. Tamizh Chelvam, M. Balamurugan
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Generalized Fractional Total Colorings of Complete Graph
Discussiones Mathematicae Graph Theory, 2013 An additive and hereditary property of graphs is a class of simple graphs which is closed under unions, subgraphs and isomorphism. Let P and Q be two additive and hereditary graph properties and let r, s be integers such that r ≥ s Then an fractional (P,
Karafová Gabriela
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Total Domination in Uniform Single Valued Neutrosophic Graph [PDF]
Neutrosophic Sets and SystemsIn graph theory, the neutrosophic graph is a new extension of the intuitionistic fuzzy graph and fuzzy graph. It offers greater accuracy and flexibility in scheduling and implementing numerous real-life issues. The introduction of neutrosophic graphs has
T.P. Sreelakshmi, K. Uma Samundesvari
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