Results 71 to 80 of about 8,236,191 (249)
Computing the forgotten topological index of four operations on graphs
AKCE International Journal of Graphs and Combinatorics, 2017 For a (molecular) graph, the first Zagreb index is equal to the sum of squares of the degrees of vertices, and the second Zagreb index is equal to the sum of the products of the degrees of pairs of adjacent vertices.
Shehnaz Akhter, Muhammad Imran
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Forcing (G,D)-number of a Graph [PDF]
, 2011 By a graph G=(V,E), we mean a finite, undirected connected graph without loops and multiple ...
Nagarajan, A. +3 more
core +1 more source
Omega Index of Line and Total Graphs
Journal of Mathematics, 2021 A derived graph is a graph obtained from a given graph according to some predetermined rules. Two of the most frequently used derived graphs are the line graph and the total graph.
Musa Demirci +3 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
On the rainbow connection numbers of line, middle, and total graphs of wheels
Electronic Journal of Graph Theory and ApplicationsAn edge-colored graph G is called rainbow connected if any two vertices in G are connected by a path whose no two edges are colored the same. The rainbow connection of G, denoted by rc(G), is the smallest number of colors needed such that G be a rainbow ...
Lyra Yulianti +2 more
doaj +1 more source
On Topological Indices of Total Graph and Its Line Graph for Kragujevac Tree Networks
Complexity, 2021 Kragujevac tree is indicated by K; K∈Kgq=s2t+1+1,s with order and size s2t+1+1 and s2t+1, respectively. In this paper, we have a look at certain topological features of the total graph and line graph of the total graph of the considered tree, i.e ...
Salma Kanwal +6 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source