Results 51 to 60 of about 741,389 (216)
On the rainbow connection numbers of line, middle, and total graphs of wheels
Electronic Journal of Graph Theory and ApplicationsAn edge-colored graph G is called rainbow connected if any two vertices in G are connected by a path whose no two edges are colored the same. The rainbow connection of G, denoted by rc(G), is the smallest number of colors needed such that G be a rainbow ...
Lyra Yulianti +2 more
doaj +1 more source
On Topological Indices of Total Graph and Its Line Graph for Kragujevac Tree Networks
Complexity, 2021 Kragujevac tree is indicated by K; K∈Kgq=s2t+1+1,s with order and size s2t+1+1 and s2t+1, respectively. In this paper, we have a look at certain topological features of the total graph and line graph of the total graph of the considered tree, i.e ...
Salma Kanwal +6 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Analysis of Z64 genetic code network [PDF]
Network BiologyThe genetic code is the set of rules defining how the sequence of nucleotides in DNA or RNA determines the specific amino acid sequence in the synthesis of protein.
Adil Akhtar, Nasrin Irshad Hussain
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Total Domination Multisubdivision Number of a Graph
Discussiones Mathematicae Graph Theory, 2015 The domination multisubdivision number of a nonempty graph G was defined in [3] as the minimum positive integer k such that there exists an edge which must be subdivided k times to increase the domination number of G.
Avella-Alaminos Diana +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source