Socio-economic inequality in small area use of elective total hip replacement in the English NHS in 1991 and 2001 [PDF]
International evidence suggests that there are substantial socio-economic inequalities in the delivery of specialist health services, even in the UK and other high-income countries with publicly funded health systems (Goddard and Smith 2001, Dixon et al.
Geoffrey Hardman +2 more
core
Central sensitisation as a determinant of patients' benefit from total hip and knee replacement [PDF]
BACKGROUND: Discrepancies exist between osteoarthritic joint changes and pain severity before and after total hip (THR) and knee (TKR) replacement. This study investigated whether the interaction between pre‐operative widespread hyperalgesia and severity
Arendt-Nielsen +25 more
core +2 more sources
3D‐Printing Aided Rapid Prototyping of Pretensioned Tensegrity Structures for Robotic Applications
Printing, injection molding, and assembly (PMA) is a method for rapid prototyping mesoscale, topologically complex, and tensioned tensegrity structures. In combination with PMA method, two mold design strategies: modular mold and compact channel layout, enable efficiency and scalability for tensegrity fabrication.
Yi Sun +3 more
wiley +1 more source
Cost-Utility Analysis of Venous Thromboembolism Prophylaxis Strategies for People Undergoing Elective Total Hip and Total Knee Replacement Surgeries in the English National Health Service [PDF]
Background: Major orthopedic surgery, such as elective total hip replacement (eTHR) and elective total knee replacement (eTKR), are associated with a higher risk of venous thromboembolism (VTE) than other surgical procedures.
Anderson +53 more
core +4 more sources
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee +9 more
wiley +1 more source
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source
Sit-to stand ground reaction force changes after hip resurfacing or total hip replacement: a pilot study [PDF]
Two groups of osteoarthritis patients had their ground reaction forces measured during a sit-to-stand task at three months post-operation. One group had a 32mm femoral head fitted during a total hip replacement procedure and the other group had a hip ...
Banaszkiewicz, Paul +4 more
core
Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve function after hip arthroplasty [PDF]
This is the protocol for a review and there is no abstract. The objectives are as follows: The aim of this review is to assess the effects of provision of assistive devices, education on hip precautions, environmental modifications and training in ADL ...
Ackerman +42 more
core +1 more source
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source

