Results 121 to 130 of about 298,488 (347)
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan+4 more
wiley +1 more source
Late infection after total hip replacement [PDF]
M Webley, M. L Snaith
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Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao+13 more
wiley +1 more source
Infection in Total Prosthetic Replacement of the Hip and Knee Joints [PDF]
N. C. Roles
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This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng+11 more
wiley +1 more source
Underrecording of osteoarthritis in United Kingdom primary care electronic health record data
Dahai Yu, Kelvin P Jordan, George Peat Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, Newcastle, UK Purpose: Primary care electronic health records are increasingly used to ...
Yu D, Jordan KP, Peat G
doaj
Aspirin-Persantin Prophylaxis in Elective total hip Replacement [PDF]
Arthur J. Silvergleid+5 more
openalex +1 more source
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo+9 more
wiley +1 more source
Letter: Risks of total hip replacement. [PDF]
Neil Shaw, Marianne Johnstone
openalex +1 more source