Results 141 to 150 of about 6,951,329 (254)

Modified scalp block and total intravenous anesthesia for frontal craniotomy in a dog with a meningioma: a technical case report. [PDF]

open access: yesVet Res Commun
Freisleben P   +8 more
europepmc   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Systemic fragility in European total intravenous anesthesia delivery and opportunities for resilient real-time decision support. [PDF]

open access: yesCommun Med (Lond)
Ionescu C   +15 more
europepmc   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv   +16 more
wiley   +1 more source

Sonoselective Transfection of Glioma Endothelium

open access: yesAdvanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski   +8 more
wiley   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu   +7 more
wiley   +1 more source

Comparison of Recovery Profile Between Total Intravenous Anesthesia and Inhalational Anesthesia in Short Surgical Procedures [PDF]

open access: yes
Background: Total Intravenous Anesthesia (TIVA) and Inhalational Anesthesia are widely used techniques in short-duration surgeries. Rapid recovery with minimal adverse effects is crucial for optimizing patient turnover and satisfaction in such procedures.
Mayuresh Hanchnal, Avinash Karekal, Reema Wali
core  

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