Results 191 to 200 of about 249,430 (314)

Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ‐PIAS1‐5/miR‐219a‐2‐3p/TEAD1 Axis

open access: yesAdvanced Science, EarlyView.
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma   +13 more
wiley   +1 more source

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong   +17 more
wiley   +1 more source

Total intravenous anesthesia for geriatric hip fracture with severe systemic disease. [PDF]

open access: yesEur J Trauma Emerg Surg, 2023
Huang YY   +9 more
europepmc   +1 more source

Mutism as a Complication of Total Intravenous Anesthesia by Propofol

open access: bronze, 2003
V Srinivasa, Peter Gerner, Sunil Eappen
openalex   +1 more source

Office-Based Outpatient Plastic Surgery Utilizing Total Intravenous Anesthesia [PDF]

open access: bronze, 2013
Colin L. Failey   +5 more
openalex   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

Anestesia total intravenosa libre de opioides en un paciente con síndrome de Joubert: caso clínico [PDF]

open access: yesRevista Chilena de Anestesia, 2020
Gonzalo M. Jacquez   +1 more
doaj   +1 more source

Neuroendocrine Stress Response and Heart Rate Variability: A Comparison of Total Intravenous Versus Balanced Anesthesia

open access: bronze, 2005
Thomas Ledowski   +6 more
openalex   +1 more source

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