Results 231 to 240 of about 249,430 (314)

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du   +21 more
wiley   +1 more source

Dual‐Atom Catalyst Au@S‐rGO for Rapid and Highly Sensitive Electrochemical Detection of Fentanyl in Serum

open access: yesAdvanced Science, EarlyView.
This study develops an Au/S‐doped reduced graphene oxide (Au@S‐rGO) sensor for rapid fentanyl detection. DFT simulations and structural analysis confirm atomically dispersed Au/S configurations, enhancing catalytic activity. The sensor achieves a 9.7 nmol L−1 detection limit, 98–104% recovery in human serum, and 85.7–93.6% consistency with mass ...
Meng Li   +9 more
wiley   +1 more source

Mitoxantrone‐Encapsulated ZIF‐8 Enhances Chemo‐Immunotherapy via Amplified Immunogenic Cell Death

open access: yesAdvanced Science, EarlyView.
Mitoxantrone (MIT)‐encapsulated zeolite imidazolate framework‐8 nanoparticles (MIT@ZIF‐8) have been designed and synthesized for chemo‐immunotherapy. This regimen enhances MIT‐induced immunogenic cell death via zinc ions‐mediated pyroptosis within tumor, and reduces immunotoxicity in tumor‐draining lymph nodes.
Junhong Li   +8 more
wiley   +1 more source

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