Results 271 to 280 of about 249,430 (314)

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

Animal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao, Binger Lu, Jinhua Yang, Xiaowan Wang, Shuxian Li, Hongbo Fu, Fenfei Gao   +6 more
wiley   +1 more source

Effects of Combined Epidural Analgesia with Total Intravenous Anesthesia on Risky Patients Underwent Major Abdominal Surgery

, 2015
Tülin Akarsu Ayazoğlu
openalex   +1 more source

Development and validation of BCG vaccine‐induced novel granulomatous liver injury preclinical animal model

Animal Models and Experimental Medicine, EarlyView.
The study successfully developed and validated a granulomatous liver injury model using a high‐dose BCG vaccine, simulating hepatic tuberculosis and autoimmune granulomatous liver diseases. Pharmacokinetic analysis examined the metabolic behavior of first‐line antitubercular drugs (isoniazid and rifampicin) and their main metabolites under conditions ...
Swati Sharma, Abhishek Moudgil, Jyoti Grewal, Pankaj Khatri, Vishal Sharma, Madhumita Premkumar, Amanjit Bal, Dibyajyoti Banerjee, Amol N. Patil   +8 more
wiley   +1 more source

Optimizing nicardipine dosage for effective control of pituitrin-induced hypertension in laparoscopic myomectomy undergoing total intravenous anesthesia. [PDF]

BMC Anesthesiol
Wang C, Zhao X, Chen Y, Xia J, Zhang X, Wang T.   +5 more
europepmc   +1 more source

A comparative study of total intravenous anesthesia with propofol/ketamine and propofol/tramadol combinations in orthopedic outpatient procedures

, 2015
Vashishta Kanchanpally, Panduranga Nagawaram   +1 more
openalex   +2 more sources

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

Animal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang, Salma Althobaiti, Braeden Pinkerton, Xin Fu, Zhenshan Jia, Kirk W. Foster, Geoffrey M. Thiele, Troy J. Plumb, Dong Wang   +8 more
wiley   +1 more source

The impact of inhalation versus total intravenous anesthesia on the immune status in patients undergoing breast cancer surgery: a double-blind randomized clinical trial (TeMP). [PDF]

Front Oncol
Kadantseva K, Subbotin V, Akchulpanov R, Berikashvili L, Yadgarov M, Zhukova L, Kvetenadze G, Svitich O, Kukina P, Kuznetsov I, Shemetova M, Smirnova A, Polyakov P, Shebankov A, Likhvantsev V.   +14 more
europepmc   +1 more source

The Use of Total Intravenous Anesthesia During Rigid Bronchoscopy And Balloon Dilatation in The Treatment Of Tracheal Stenosis: A Report of 4 Cases

, 2015
Canan Salman Önemli, Deniz Ayhan Çatal
openalex   +2 more sources

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

Animal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo, Siyethemba Bhengu, Kobus Venter, Yolandy Lemmer, Shayne Mason   +4 more
wiley   +1 more source

Comparison of Ciprofol-Based and Propofol-Based Total Intravenous Anesthesia on Microvascular Decompression of Facial Nerve with Neurophysiological Monitoring: A Randomized Non-Inferiority Trial. [PDF]

Drug Des Devel Ther
Zhu T, Kang F, Han MM, He F, Jiang S, Hao LN, Huang X, Li J.   +7 more
europepmc   +1 more source