Results 271 to 280 of about 163,866 (351)

Dexmedetomidine-methadone-ketamine versus dexmedetomidine-methadone-alfaxalone for cats undergoing ovariectomy [PDF]

Adami, C, Donnelly, T M, Dresco, T, Fernandez-Parra, R, Zilberstein, L   +4 more
core   +1 more source

Redox‐Programmed Activation of a Dual‐Modal Probe for High‐Fidelity Tumor Delineation and Image‐Guided Surgery

Advanced Science, EarlyView.
This study presents a glutathione (GSH)‐activatable dual‐modality probe (GAP9) with a redox‐tuned activation window for precise tumor detection. It remains quenched (“OFF”) in normal tissue yet activates specifically in tumors for T1‐weighted magnetic resonance imaging (MRI) preoperative mapping and near‐infrared II (NIR‐II) fluorescence intraoperative
Haohao Yan, Yanbin Feng, Qian Jia, Ruili Zhang, Zhongliang Wang   +4 more
wiley   +1 more source

Total intravenous anesthesia using midazolam and dexmedetomidine as substitutes for propofol in a pediatric patient with egg allergy and a family history of malignant hyperthermia. [PDF]

Saudi J Anaesth
Inoue M, Morita M.
europepmc   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

Comparing subjective quality of recovery between remimazolam- and propofol-based total intravenous anesthesia for surgical procedures: a meta-analysis. [PDF]

Syst Rev
Hung KC, Wang WT, Liu WC, Hsu CW, Huang YT, Wu JY, Chen IW.   +6 more
europepmc   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Benefit of Gastro™ Laryngeal Mask Airway® during Total Intravenous Anesthesia for Endoscopic Retrograde Cholangiopancreatography: A Randomized Controlled Study.

Ann Afr Med
Archana KN, Subramanian A, Kumar PH, Kumararadhya GB, Nandeesh HP, Shivakumar KG.   +5 more
europepmc   +1 more source

Impact of general anesthesia on postoperative complications in orthognathic surgery: a retrospective comparison of total intravenous anesthesia versus volatile anesthesia. [PDF]

Sci Rep
Aijima R, Miura D, Takamori A, Kamohara A, Danjo A, Sakaguchi Y, Yamashita Y.   +6 more
europepmc   +1 more source