Objectives The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing (RNAseq) in vastus lateralis muscle, resulting in 523 participants (56% female ...
Daniel S. Evans +7 more
wiley +1 more source
The risk of revision using tourniquet or not in primary total knee replacement: an observational study from the Swedish Knee Arthroplasty Register. [PDF]
W-Dahl A +3 more
europepmc +1 more source
MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez +13 more
wiley +1 more source
Refractory Chronic Knee Pain After Total Knee Replacement Successfully Treated With L4 Dorsal Root Ganglion Pulsed Radiofrequency. [PDF]
Omar M, AlShehhi BM, Al Ali S.
europepmc +1 more source
Background Calcium pyrophosphate deposition (CPPD) disease is a heterogeneous condition and is frequently misdiagnosed due to the different clinical presentations and variable disease progression. Aim of this study is to identify clinical phenotypes of CPPD disease by integrating real‐world data from two datasets. Methods Data from the COLCHICORT trial
Greta Pellegrino +20 more
wiley +1 more source
Massive Hemorrhagic Blisters following Bilateral Total Knee Replacement: A Case Report. [PDF]
Latha DN, Janakiraman B.
europepmc +1 more source
Continuous Hemodynamic Monitoring and Goal-Directed Therapy for Optimization in Total Knee Replacement: A Prospective Observational Study. [PDF]
Christofis C +6 more
europepmc +1 more source
Simultaneous bilateral total knee replacement in a patient with achondroplasia and severe varus deformity: a case report. [PDF]
Chernov D +6 more
europepmc +1 more source
Similar patient-reported outcomes 6 months after unicompartmental and total knee replacement for osteoarthritis: a prospective cohort study of 60,145 patients from the Australian Orthopaedic Association National Joint Replacement Registry. [PDF]
Fidler HL +5 more
europepmc +1 more source
A Systematic Review of International Evidence to Inform Occupational Therapy Practice Guidelines for Total Knee Replacement in the Korean Health System. [PDF]
Kim JA, Ha SK, Jung MY.
europepmc +1 more source

