Results 41 to 50 of about 8,808,141 (242)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Scaled weighted total least-squares adjustment for partial errors-in-variables model
Journal of Geodetic Science, 2016 Scaled total least-squares (STLS) unify LS, Data LS, and TLS with a different choice of scaled parameter. The function of the scaled parameter is to balance the effect of random error of coefficient matrix and observation vector for the estimate of ...
Zhao J.
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
On the condition number of the total least squares problem [PDF]
Numerische Mathematik, 2013 27 pages, 2 figures.
Zhongxiao Jia, Bingyu Li
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A Stochastic Total Least Squares Solution of Adaptive Filtering Problem
The Scientific World Journal, 2014 An efficient and computationally linear algorithm is derived for total least squares solution of adaptive filtering problem, when both input and output signals are contaminated by noise.
Shazia Javed, Noor Atinah Ahmad
doaj +1 more source
A Contribution to the Conditioning of the Total Least-Squares Problem [PDF]
SIAM Journal on Matrix Analysis and Applications, 2011 We derive closed formulas for the condition number of a linear function of the total least squares solution. Given an over determined linear system Ax=b, we show that this condition number can be computed using the singular values and the right singular vectors of [A,b] and A.
Baboulin, Marc, Gratton, Serge
openaire +6 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Weighted Total Least Squares (WTLS) Solutions for Straight Line Fitting to 3D Point Data
Mathematics, 2020 In this contribution the fitting of a straight line to 3D point data is considered, with Cartesian coordinates xi, yi, zi as observations subject to random errors.
Georgios Malissiovas +3 more
doaj +1 more source
Chinese Journal of Mechanical Engineering, 2023 Online parameter identification is essential for the accuracy of the battery equivalent circuit model (ECM). The traditional recursive least squares (RLS) method is easily biased with the noise disturbances from sensors, which degrades the modeling ...
Xinghao Du +6 more
doaj +1 more source