Results 41 to 50 of about 379,174 (254)

Inspiratory capacity‐to‐total lung capacity ratio and dyspnoea predict exercise capacity decline in COPD [PDF]

Respirology, 2015
AbstractBackground and objectiveExercise capacity decline is a predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). Static pulmonary hyperinflation is a key determinant of exercise performance, but its effect on the longitudinal decline in exercise capacity remains unknown. We aimed to study the relationship between the
Ramon, Maria Antonia, Ferrer, Jaume, Gimeno Santos, Elena, 1980-, Donaire González, David, Rodríguez, Esther, Balcells Vilarnau, Eva, 1967-, De Batlle, Jordi, Benet, Marta, Guerra, Stefano, Sauleda Roig, Jaume, Ferrer, Antoni-Lluc, 1942-, Farrero, Eva, Gea Guiral, Joaquim, Barberà, Joan Albert, Agustí García-Navarro, Àlvar, Rodríguez-Roisin, Robert, Antó i Boqué, Josep Maria, García Aymerich, Judith, PAC-COPD Study Group   +18 more
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An accurate and rapid radiographic method of determining total lung capacity [PDF]

Thorax, 1972
The accuracy and reliability of Barnhard9s radiographic method of determining total lung capacity have been confirmed by several groups of investigators. Despite its simplicity and general reliability, it has several shortcomings, especially when used in large-scale epidemiological surveys. Of these, the most serious is related to film technique; thus,
R B, Reger, A, Young, W K, Morgan
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Compatibility analysis of total lung capacity values measured by segmentation with computed tomography and helium dilution method

Annals of Thoracic Medicine
BACKGROUND: Accurate assessment of lung volumes is essential for diagnosing ventilatory defects and managing pulmonary diseases such as interstitial lung diseases (ILDs) and chronic obstructive pulmonary disease (COPD).
Aysegul Erinc, Ali Kirac, Damla Azakli, Banu Kahriman, Celal Satici, Erdogan Cetinkaya   +5 more
doaj   +1 more source

Variation of densitometry on computed tomography in COPD--influence of different software tools. [PDF]

PLoS ONE, 2014
Quantitative multidetector computed tomography (MDCT) as a potential biomarker is increasingly used for severity assessment of emphysema in chronic obstructive pulmonary disease (COPD).
Mark O Wielpütz, Diana Bardarova, Oliver Weinheimer, Hans-Ulrich Kauczor, Monika Eichinger, Bertram J Jobst, Ralf Eberhardt, Marcel Koenigkam-Santos, Michael Puderbach, Claus P Heussel   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Thoracic ultrasonography and pulmonary function tests in assessing lung function in acromegaly: a prospective matched case-control study

Monaldi Archives for Chest Disease
Acromegaly is a rare disease characterized by elevated levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), leading to changes in various organ systems.
Ayshan Mammadova, Meric Coskun, Zeynep Yalcinkaya, Ilhan Yetkin, Nurdan Kokturk   +4 more
doaj   +1 more source

Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer

Chinese Journal of Lung Cancer, 2013
Background and objective To those patients with advanced lung cancer, the ultimate objective is to improve the curative effect and quality of life, lung function indexes are an important factor.
Hui GE, Zhenghua JIANG, Qian HUANG, Muyun ZHU, Jie YANG   +4 more
doaj   +1 more source