Results 171 to 180 of about 8,795,233 (257)
Quality of life and anorectal function in rectal cancer patients undergoing immunotherapy-based total neoadjuvant therapy: a comparison of organ preservation and radical surgery. [PDF]
He L +28 more
europepmc +1 more source
ABSTRACT Background Robust outcome data for anterior skull base cutaneous squamous cell carcinoma (cSCC) are limited, particularly as emerging therapies reshape management. We evaluated survival and prognostic factors following craniofacial resection. Methods Retrospective multi‐institutional case‐series (1995–2015) of patients who underwent skull base
Michael J. C. Schachtel +52 more
wiley +1 more source
De-escalated total neoadjuvant therapy for the non-operative management of rectal cancer: Results of the NOM-3/TNT prospective cohort study. [PDF]
Skrzypiec B +10 more
europepmc +1 more source
ABSTRACT Background Transoral robotic surgery (TORS) is widely used in management of early‐stage primary oropharyngeal squamous cell carcinoma (OPSCC). Tumors involving the glossotonsillar sulcus (GTS) are hypothesized to confer worse oncological outcomes compared to those situated in the rest of the oropharynx, with a paucity of evidence to support ...
Johan S. Nilsson +9 more
wiley +1 more source
Total Neoadjuvant Therapy for Rectal Cancer: Why Japan Says "Not Yet". [PDF]
Uehara K +4 more
europepmc +1 more source
ABSTRACT Introduction A Phase II trial demonstrated that neoadjuvant cemiplimab was associated with pathologic complete response (pCR) in 51% of patients with locoregionally advanced cutaneous squamous cell carcinoma (cuSCC). We evaluated real‐world radiographic and pathologic responses to neoadjuvant cemiplimab and assessed radiologic–pathologic ...
Whitney Jin +14 more
wiley +1 more source
A multicohort, biomarker-driven phase 2 trial of personalized total neoadjuvant therapy with targeted agents for high-risk rectal cancer (The TRAINER study). [PDF]
Ma T +29 more
europepmc +1 more source
ABSTRACT Background Neoadjuvant immunotherapy is an emerging treatment for patients with head and neck cancer. Given the heterogeneity of response, novel methods of intraoperative tumor and margin assessment warrant investigation. Methods A 55‐year‐old male presented with a cT3N2c supraglottic squamous cell carcinoma with a combined positive score of 5.
Joaquin Austerlitz +7 more
wiley +1 more source
Risk-Adapted Selective Elective Nodal Irradiation in the Total Neoadjuvant Therapy Era for Rectal Cancer. [PDF]
Yeo SG +5 more
europepmc +1 more source
ABSTRACT Background The safety of vasopressors for managing intraoperative hypotension remains debated. This study evaluated complications associated with vasopressor use and fluid administration in oral cavity cancer free flap surgery. Methods Retrospective review of 826 patients who received oral cavity cancer free flap reconstruction from 2008 to ...
Harrison Gao +18 more
wiley +1 more source

