Results 211 to 220 of about 8,795,233 (257)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment

open access: yesiNew Medicine, EarlyView.
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su   +7 more
wiley   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci   +4 more
wiley   +1 more source

Safety and Efficacy of a Sandwich Total Neoadjuvant Therapy Strategy for Low-Risk Distal Locally Advanced Rectal Cancer: Results From the TESS Phase II Trial. [PDF]

open access: yesMedComm (2020)
Liu S   +17 more
europepmc   +1 more source

Application of MR Cytometry in Predicting Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer: A Comparative Study

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MR cytometry imaging is developed to characterize in vivo microstructures. Its clinical value in predicting pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) for breast cancer remains unknown. Purpose To implement MR cytometry to predict pCR for breast cancer and compare the performance of different ...
Jie Ding   +10 more
wiley   +1 more source

Total neoadjuvant therapy for locally advanced rectal cancer: barriers to implementation in real-world practice. [PDF]

open access: yesJ Cancer Res Clin Oncol
Steike DR   +11 more
europepmc   +1 more source

Comparison of Continuous‐Time Random Walk and Fractional Order Calculus Diffusion Models for Preoperative Breast Lesion Characterization: Diagnosis, Biomarker Prediction and Molecular Subtyping

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Accurate preoperative characterization of breast lesions is important for individualized management. The conventional monoexponential (Mono) model has limited ability to capture the complex microstructure of lesions. Non‐Gaussian diffusion models, including continuous‐time random walk (CTRW) and fractional‐order calculus (FROC), may
Yimeng Cao   +10 more
wiley   +1 more source

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