Training for Rectal Resection in the Era of Total Neoadjuvant Therapy and Organ Preservation: Safeguarding Competence as Operative Casemix Evolves. [PDF]
Gosavi R +5 more
europepmc +1 more source
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Pretreatment Staging FDG PET-Derived Radiomic Score Predicts Progression-Free Survival in Locally Advanced Rectal Cancer Treated with Total Neoadjuvant Therapy. [PDF]
Kucuker KA +5 more
europepmc +1 more source
Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su +7 more
wiley +1 more source
Total Neoadjuvant Therapy, Organ Preservation and Beyond: A State-of-the-Art Systematic Review and Critical Appraisal of Locally Advanced Rectal Cancer Management. [PDF]
Ismaili N.
europepmc +1 more source
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci +4 more
wiley +1 more source
Safety and Efficacy of a Sandwich Total Neoadjuvant Therapy Strategy for Low-Risk Distal Locally Advanced Rectal Cancer: Results From the TESS Phase II Trial. [PDF]
Liu S +17 more
europepmc +1 more source
ABSTRACT Background MR cytometry imaging is developed to characterize in vivo microstructures. Its clinical value in predicting pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) for breast cancer remains unknown. Purpose To implement MR cytometry to predict pCR for breast cancer and compare the performance of different ...
Jie Ding +10 more
wiley +1 more source
Total neoadjuvant therapy for locally advanced rectal cancer: barriers to implementation in real-world practice. [PDF]
Steike DR +11 more
europepmc +1 more source
ABSTRACT Background Accurate preoperative characterization of breast lesions is important for individualized management. The conventional monoexponential (Mono) model has limited ability to capture the complex microstructure of lesions. Non‐Gaussian diffusion models, including continuous‐time random walk (CTRW) and fractional‐order calculus (FROC), may
Yimeng Cao +10 more
wiley +1 more source

