Results 41 to 50 of about 9,973,923 (297)

Assessment of hydrology, sediment and particulate organic carbon yield in a large agricultural catchment using the SWAT model [PDF]

open access: yes, 2011
The Soil and Water Assessment Tool (SWAT, 2005) was used to simulate discharge and sediment transport at daily time steps within the intensively farmed Save catchment in south-west France (1110 km2).
Simeoni-Sauvage, Sabine   +6 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Forestry impact on water quality: a landscape perspective on dissolved organic carbon [PDF]

open access: yes, 2013
Dissolved organic carbon (DOC) is a fundamental variable defining boreal stream ecosystems. In this thesis the impact of forestry practices that are commonly performed in the boreal regions of Scandinavia for stream water quality were evaluated.
Schelker, Jakob
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Using C-Tool to simulate soil carbon and radiocarbon development [PDF]

open access: yes, 2001
Tho model framework C-TOOL was used to simulate soil carbon and radiocarbon development.
Petersen, B.M., Berntsen, J.
core   +1 more source

Greater mineral and aggregate protection for organic carbon in the soil amended by weathered coal than by biochar: Based on a 3-year field experiment

open access: yesGeoderma, 2023
Soil carbon pool stability plays an important role in reaching carbon neutrality and mitigating global warming. Applying soil amendments is a practical strategy in agricultural production to improve soil environment.
Xiaoyuan Zhang   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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