Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Antioxidant Supplementation Reduces <i>In Vitro</i> Oxidant Generation in Neonatal Total Parenteral Nutrition Solutions. [PDF]
Karthigesu K, Bertolo RF, Brown RJ.
europepmc +1 more source
Cancer pain: current practice and emerging targets
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu +7 more
wiley +1 more source
Longitudinal Plasma Metabolomics by GC-MS and LC-MS During Total Parenteral Nutrition After Gastrointestinal Surgery. [PDF]
Konuklu D +7 more
europepmc +1 more source
The impact of preoperative total parenteral nutrition on the surgical complications of Crohn's disease: A retrospective cohort study. [PDF]
Traiki TAB +7 more
europepmc +1 more source
Abstract Aims Glycaemic abnormalities during hospitalization are common and linked to morbidity and mortality, yet little is known about how deviations from guideline‐recommended insulin dosing affect outcomes. The aim of this study is to examine whether deviation from an expected insulin dose in non‐critically ill hospitalized adults with type 2 ...
Hussein Zaitoon +5 more
wiley +1 more source
Reversal of Acute Liver Injury Post-Roux-en-Y Gastric Bypass With Total Parenteral Nutrition. [PDF]
Daou C +4 more
europepmc +1 more source
Abstract Aims To compare person‐reported outcomes on point‐of‐care (POC) fingerstick glucose monitoring (FSGM) with POC continuous glucose monitoring systems (CGMS) in adults admitted to surgical wards. The primary outcome was convenience; the secondary outcome was satisfaction with diabetes‐related treatment.
Tine Lumbye Thomsen +6 more
wiley +1 more source
Evaluating a Clinical Decision Support System for Optimizing Total Parenteral Nutrition in Adult Oncology Patients. [PDF]
Foscolou A, Kostara C, Gioxari A.
europepmc +1 more source

