Results 141 to 150 of about 6,669,320 (385)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

The reality of the application of Total Quality Management from the standpoint of supervisors National Endowment for the provision and reserve in M’SILA model

open access: yesالأستاذ, 2018
The present study addressed the issue of the overall quality of the Algerian enterprise management through the viewpoint of some supervisors, so that the study was conducted on a sample of ten supervisors National Fund for the provision and reserve in M’
Asst.Prof.Dr. Taha Saleh Hamou   +1 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

THE MAIN PRINCIPLES OF TOTAL QUALITY MANAGEMENT [PDF]

open access: yesChallenges of the Knowledge Society, 2016
Nowadays the industry is one of the main economic sectors, with a major contribution to achieving and maintaining a high rate of economic growth. The processing industry operation to high economic performance requires changes in structural terms, the re ...
Andrei DIAMANDESCU
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

THE INFLUENCE OF ORGANISATIONAL CULTURE ON THE TOTAL QUALITY MANAGEMENT PROGRAMME PERFORMANCE

open access: yesInvestigaciones Europeas de Dirección y Economía de la Empresa, 2012
This paper aims to examine the relationships between different types of cultures and effectiveness in Total Quality Management (TQM) implementation.
Roldán, José L.   +2 more
doaj   +1 more source

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