Results 151 to 160 of about 6,669,320 (385)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Total Quality Management (TQM) in Hungary [PDF]

open access: yes, 1990
In up-to-date manufacturing, industrial quality has proven to be a key competitive advantage. An active market position and profits are associated with high quality products and services.
Asboth, T.   +4 more
core  

Towards an Ontology of Traceable Impact Management in the Food Supply Chain [PDF]

open access: yesarXiv
The pursuit of quality improvements and accountability in the food supply chains, especially how they relate to food-related outcomes, such as hunger, has become increasingly vital, necessitating a comprehensive approach that encompasses product quality and its impact on various stakeholders and their communities.
arxiv  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Sustainable Management and Total Quality Management in Public Organizations with Outsourcing [PDF]

open access: yes
The aim of this paper is to explore how Total Quality Management (TQM) can act as a foundation and key catalyst for developing Sustainable Management and Corporate Social Responsibility (CSR) within Public Organizations.
Gazzola Patrizia, Pellicelli Michela
core  

An investigation into the use of quality management techniques in NZ IT projects : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Information Systems at Massey University [PDF]

open access: yes, 2006
The risks in an IT project are very high both because of its complexity and also because the context of rapidly-developing technology leads to a high degree of uncertainty.
Xu, RuiLin
core  

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