Results 41 to 50 of about 217,945 (313)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Total reaction cross sections for 8Li + 90Zr at near-barrier energies

, 2015
Total reaction cross sections for the radioactive nucleus 8Li on 90Zr are reported at the near-barrier energies of 18.5 and 21.5MeV, derived from quasi-elastic scattering measurements.
Soukeras, V., SORAMEL, FRANCESCA, D. Pierroutsakou, Manea, C., O. Sgouros, C. Manea, Strano, E., La Commara, M., Y.X. Watanabe, V. Soukeras, Boiano, C., C. Boiano, I. Martel, MAZZOCCO, MARCO, D. Torresi, A.M. Sánchez-Benítez, L. Acosta, M. La Commara, A. Boiano, Aslanoglou, X., A. Trzcinska, A. Pakou, C. Signorini, G. Marquinez-Duran, Keeley, N., E. Strano, LA COMMARA, MARCO, Marquinez Duran, G., N. Keeley, E. Stiliaris, PARASCANDOLO, CONCETTA, TORRESI, DOMENICO MARIO, H. Yamaguchi, Sgouros, O., Torresi, D., M. Cavallaro, Carbone, D., Watanabe, Y. X., Soramel, F., K. Rusek, Mazzocco, M., F. Soramel, Pierroutsakou, D., Rusek, K., Boiano, A., Stiliaris, E., Acosta, L., Cavallaro, M., Trzcinska, A., Sánchez Benítez, A. M., SIGNORINI, COSIMO, M. Mazzocco, C. Parascandolo, Martel, I., Parascandolo, C., STRANO, EMANUELE, D. Carbone, Pakou, A, X. Aslanoglou, Yamaguchi, H., Grebosz, J., J. Grebosz, Signorini, C.   +62 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of Neutron Capture Cross Sections and Covariances on 99Tc and 129I in the keV Energy Region

EPJ Web of Conferences, 2016
Neutron capture cross sections and covariances on radioactive 99Tc and 129I have been required for developing environmental load-reducing technology. Their evaluation was performed by using nuclear reaction calculation code CCONE and Baysian code KALMAN ...
Iwamoto Nobuyuki
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Breakup of 8B+natZr at the sub-barrier energy of 26.5 MeV [PDF]

EPJ Web of Conferences
In our systematic research on reactions with weakly bound nuclei at suband nearbarrier energies, we have studied the system 8B+natZr at the sub-barrier energy of 26.5 MeV.
Palli K., Pakou A., Moro A. M., O’ Malley P. D., Acosta L., Sántzez-Bénitez A., Souliotis G., Aguilera E. F., Andrade E., Godos D., Sgouros O., Soukeras V., Agodi C., Bailey T. L., Bardayan D. W., Boomershine C., Brodeur M., Cappuzzello F., Caramichael S., Cavallaro M., Dede S., Dueñas J.A., Henning J., Lee K., Porter W.S., Rivero F., von Seeger W.   +26 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Breakup, fusion, and elastic scattering analysis of the 8B + 58Ni system at low energies with the continuum-discretized coupled channels method

EPJ Web of Conferences, 2014
We have performed continuum-discretized coupled channels (CDCC) calculations of the breakup of 8B on 58Ni in the energy interval 10 – 26 MeV in the c.m. system.
Belyaeva T. L., Amador-Valenzuela P., Aguilera E. F., Martinez-Quiroz E., Kolata J. J.   +4 more
doaj   +1 more source