Results 131 to 140 of about 2,588,337 (304)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

The effect of hydro-alcoholic extract of Salvia officinalis L. on the electrolytes and serum proteins in adult diabetic male rat

open access: yesFiyz̤, 2018
Background: Diabetes is the result of functional impairment of insulin secretion. The aim of this study was to examine the effect of the Salvia officinalis (SO) extract on serum levels of albumin, total protein and serum sodium and potassium electrolytes.
Maryam Mirchenari, Farnaz Tavakoli
doaj  

Diet supplementation with Saccharomyces cerevisiae influences the electrophoretic parameters in blood in young Charolaise bulls

open access: yesJournal of Veterinary Research
The objective of the research was to investigate the effect of Saccharomyces cerevisiae supplementation on some acute-phase proteins, haptoglobin and all electrophoretic parameters in young Charolaise bulls.
Arfuso Francesca   +6 more
doaj   +1 more source

Vitamin D and calcium metabolism in horses in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Institute of Veterinary, Animal and Biomedical Sciences (IVABS), Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2016
The physiology of vitamin D in horses has not been studied in great depth. Few studies on vitamin D metabolites (25OHD2, 25OHD3, and 1,25(OH)2D) and their relationship to other serum analytes exist. In addition, some studies suggest that equine vitamin D
Azarpeykan, Sara
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Вариабилност на общия белтък в кръвен серум на овце І. Тенденции в породната изменчивост

open access: yesЖивотновъдни науки, 2012
The aim of the study was to determine the trends in breed changeability of the total protein level in blood serum of sheep and to evaluate the role of breed appurtenance in the variability of the parameter discussed.
КРАСИМИР БОЙЧЕВ   +1 more
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Aboralis pótgyomor prospektív randomizált összehasonlítása hagyományos orális pótgyomorral totális gastrectomia után = Prospective randomised comparison of aboral pouch with conventional oral pouch after total gastrectomy. [PDF]

open access: yes, 2008
Prospektív randomizált vizsgálat keretében hasonlítottunk össze totális gastrectomia után két rekonstrukció típust, az aborális és az orális pótgyomrot a duodenális passzázs megtartásával. 28 beteg lépett be a tanulmányba. A betegeknél antropometriai és
Cseke, László   +4 more
core  

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