Results 91 to 100 of about 9,395,070 (255)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Low-voltage variable capacitance diode

, 2004
Low-voltage variable capacitance diode Product ...
Voltage Controlled Oscillators (vco
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Step-Up 25-Level Inverter Topology for Photovoltaic Systems

CES Transactions on Electrical Machines and Systems
Integration of renewable energy sources into power systems requires efficient multilevel inverters, capable of producing high-quality output voltage with low total harmonic distortion (THD).
Fatemeh Esmaeili, Hamid Reza Koofigar, Frede Blaabjerg   +2 more
doaj   +1 more source

Mechanisms of defibrillation by standing waves in the bidomain ventricular tissue with voltage applied in an external bath

, 2009
Standing waves of depolarisation produced by periodic low-voltage driving eliminate propagation activity in the heart, thus providing a defibrillating effect.
Zhang, Henggui, Aslanidi, O.V., Boyett, M.R., Benson, A.P., Henggui Zhang, Mark R. Boyett, Oleg V. Aslanidi, Alan P. Benson   +7 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Demo 09-28 Rubber Tube Standing Waves

, 2001
A variable frequency motor is used to vibrate the end of a long rubber tube, creating standing waves, as seen in Figure 1 for the third harmonic mode.

core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A Novel Nine-Level Quadruple Boost Inverter for Electric Vehicle Applications

IEEE Access
Lithium cells are commonly arranged in series and parallel configurations to fulfil the specific voltage and current necessities within electric vehicles (EVs).
G. Dhasharatha, Md. Haseeb Khan, B. Mangu   +2 more
doaj   +1 more source