Results 101 to 110 of about 9,395,070 (255)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
While the conventional topologies of multilevel inverters (MLIs) operate with unity voltage gain, switched capacitors-based MLIs (SCMLIs) offer a solution to realize an inherent voltage gain of more than one, thereby stepping up the voltage in the ...
Niraj Kumar Dewangan +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
In this study, a 13‐level switched‐capacitor inverter with triple voltage gain is proposed. The proposed structure generates 13‐level output voltage using only one DC source, eleven switches, and three capacitors.
Masoumeh Derakhshandeh +3 more
doaj +1 more source
This paper proposes a double source double diode double switch (DSDDDS) multilevel inverter to generate positive voltage and a connecting polarity changing circuit of an H-bridge inverter to generate negative voltage.
V. Kubendran +4 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
We propose a new technique for the combined voltage scaling of processors and communication links, taking into account dynamic as well as leakage power consumption.
Eles, Petru +4 more
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Photo, portrait of Standing Bear, the chief of the Ponca Indians whose tribe was moved to Indian Territory in Oklahoma in 1877. Wanting to return to his homeland in Nebraska, he led a number of his people on a hard and dangerous journey back.
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

