The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
The Interplay between Error, Total Variation, Alpha-Entropy and Guessing: Fano and Pinsker Direct and Reverse Inequalities. [PDF]
Entropy (Basel), 2023 Rioul O.
europepmc +1 more source
Mixed-Derivative Total Variation
The formulation of norms on continuous-domain Banach spaces with exact pixel-based discretization is advantageous for solving inverse problems (IPs). In this paper, we investigate a new regularization that is a convex combination of a TV term and the $\M(\R^2)$ norm of mixed derivatives.
Guillemet, Vincent, Unser, Michael
openaire +2 more sources
Non-convex Total Variation Regularization for Convex Denoising of Signals
Journal of Mathematical Imaging and Vision, 2020 I. Selesnick +3 more
semanticscholar +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Bilateral Weighted Relative Total Variation for Low-Dose CT Reconstruction. [PDF]
J Digit Imaging, 2023 He Y, Zeng L, Chen W, Gong C, Shen Z.
europepmc +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Identification of the methotrexate resistance-related diagnostic markers in osteosarcoma via adaptive total variation netNMF and multi-omics datasets. [PDF]
Front Genet, 2023 Jiang Z +5 more
europepmc +1 more source
A Fast Total Variation Minimization Method for Image Restoration
, 2008 Yumei Huang +2 more
openalex +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source