Results 151 to 160 of about 10,393,467 (307)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Interplay between Error, Total Variation, Alpha-Entropy and Guessing: Fano and Pinsker Direct and Reverse Inequalities. [PDF]
Entropy (Basel), 2023 Rioul O.
europepmc +1 more source
Total $$\mathbb {A}$$-variation flows
Annali di Matematica Pura ed Applicata (1923 -)Abstract We study the $$L^2$$ -gradient flows, $$\partial _t u-\operatorname {div}(\textrm{D}f(x,\mathbb {A}u))=0$$ , of functionals of the type
openaire +2 more sources
, 2016 In this paper, we propose a novel approach to hyperspectral image super-resolution by modeling the global spatial-and-spectral correlation and local smoothness properties over hyperspectral images.
Cao, Wenfei +4 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Zero-exemplar deep continual learning for crop disease recognition: a study of total variation attention regularization in vision transformers. [PDF]
Front Plant Sci, 2023 Wang B.
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Bilateral Weighted Relative Total Variation for Low-Dose CT Reconstruction. [PDF]
J Digit Imaging, 2023 He Y, Zeng L, Chen W, Gong C, Shen Z.
europepmc +1 more source
focusing on total variation minimization
, 2019 학위논문(박사) - 한국과학기술원 : 수리과학과, 2019.8,[vi, 162 p. :]This dissertation is concerned with domain decomposition methods for convex optimization in image processing. In particular, we focus on total variation minimization which is one of the standard techniques
Park, Jongho
core +1 more source