Results 131 to 140 of about 10,393,467 (307)
Licensing Reflexivity: Unity and variation among selected Uralic languages [PDF]
This dissertation analyzes the reflexivity patterns in Uralic languages from the point of view of a minimalist approach to binding. The languages under consideration are five Uralic languages spoken in the Russian Federation: Meadow Mari, Komi-Zyrian ...
Volkova, A.A. +3 more
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Total Variation Meets Differential Privacy
The framework of approximate differential privacy is considered, and augmented by leveraging the notion of ``the total variation of a (privacy-preserving) mechanism'' (denoted by $\eta$-TV).
Issa, Ibrahim, Ghazi, Elena
core +2 more sources
Limit theorems for bipower variation in financial econometrics [PDF]
In this paper we provide an asymptotic analysis of generalised bipower measures of the variation of price processes in financial economics. These measures encompass the usual quadratic variation, power variation and bipower variations which have been ...
Neil Shephard +3 more
core
Studies on seasonal variation in metabolic rate related to changes in body composition with particular reference to shorebirds (Charadrii) [PDF]
The basal metabolic rate of three species of shorebird was measured throughout the non-breeding season. These measurements were related to change in body mass and body composition.
Scott, Ian Alexander
core
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Solving total variation problems is fundamentally important for many computer vision tasks, such as image smoothing, optical flow estimation and 3D surface reconstruction. However, the traditional iterative solvers require a large number of iterations to
Yuanhao Gong
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

