Results 201 to 210 of about 17,556,704 (381)

Predicting human detection performance in magnetic resonance imaging (MRI) with total variation and wavelet sparsity regularizers. [PDF]

Proc SPIE Int Soc Opt Eng, 2022
O'Neill AG, Lingala SG, Pineda AR.
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Impact of Total Variation Regularized Expectation Maximization Reconstruction on ⁶⁸Ga-DOTA-TATE PET/CT Images in Patients With Neuroendocrine Tumor. [PDF]

Front Med (Lausanne), 2022
Liu L, Liu H, Xu S, Zhang S, Tao Y, Mok GSP, Chen Y.   +6 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

TVL1-IMPT: Optimization of Peak-to-Valley Dose Ratio Via Joint Total-Variation and L1 Dose Regularization for Spatially Fractionated Pencil-Beam-Scanning Proton Therapy. [PDF]

Int J Radiat Oncol Biol Phys, 2023
Zhang W, Li W, Lin Y, Wang F, Chen RC, Gao H.   +5 more
europepmc   +1 more source

A Fast High-Order Total Variation Minimization Method for Multiplicative Noise Removal [PDF]

, 2013
Xiao-Guang Lv, Le Jiang, Jin Huang, Jun Liu   +3 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A projection-domain iterative algorithm for metal artifact reduction by minimizing the total-variation norm and the negative-pixel energy. [PDF]

Vis Comput Ind Biomed Art, 2022
Zeng GL.
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Directional adaptive mode total variation for seismic data denoising. [PDF]

Sci Rep
Banjade TP, Zhou C, Yang Y, Li H, Deng J.   +4 more
europepmc   +1 more source