Results 121 to 130 of about 8,388,417 (298)
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
, 2000 The total variation diminishing with artificial compression (TVD/AC) scheme is applied to the lattice Boltzmann multiphase model in order to introduce a new technique to solve the traditional lattice Boltzmann equation.
S Teng (13600789) +2 more
core
Nonlinear Dynamics of Displacement Fronts in Two-Phase Flows Propagating Through Porous Media
MathematicsA generalized mathematical model is constructed to describe the isothermal two-phase flow of a three-component system and to investigate light non-aqueous phase liquid (LNAPL) displacement during surfactant-enhanced remediation in vertical porous media ...
Diana Kerimbekova +3 more
doaj +1 more source
Inlet effects on roll-wave development in shallow turbulent open-channel flows
Journal of Hydrology and Hydromechanics, 2016 The present work investigates the effect of the flow profile induced by an inlet condition on the roll-wave evolution in turbulent clear-water flows. The study employs theoretical and numerical analyses.
Campomaggiore Francesca +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Best Approximation and Cyclic Variation Diminishing Kernels
, 2008 where the kernel K(x, y) is Strictly Cyclic Variation Diminishing, and related problems including periodic generalized perfect splines. For various approximation problems of this type, we show the uniqueness of the best approximation and characterize the
Oleg Davydov, Allan Pinkus
core
GeodermaThe concentrations of available phosphorus (P) and potassium (K) in soil can be estimated by soil spectroscopy, and with sufficient sampling can be mapped to guide farmers to apply fertilizer at variable rates.
T.S. Breure +5 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
There is more: Variation in expletive constructions in Dutch [PDF]
, 2018 This thesis is concerned with expletive clauses in Dutch. An example of such a construction follows in (1). (1) Er loopt iemand op straat. There walks someone on street ‘Someone is walking in the street.’ In this sentence the expletive pronoun er ‘there’
Wesseling, F. +2 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source