Results 101 to 110 of about 8,388,417 (298)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Variation diminishing property of densities of uniform generalized order statistics

open access: yes
Generalized order statistics, Variation diminishing property, Meijer’s G-function,
Mariusz Bieniek
core   +1 more source

DETECTION OF QTL AFFECTING FLEECE TRAITS ON CHI 19 IN ANGORA GOATS

open access: yesTropical and Subtropical Agroecosystems, 2009
Some previous studies have indicated the presence of genes or gene families involved in fleece traits in different species. The aim of the present study was to search Quantitative Traits Loci (QTL) associated with fleece qualitative and quantitative ...
E. M. Cano   +7 more
doaj  

A Semi-Coupled Model for Morphological Flow Simulation in River Bend

open access: yesJournal of Applied Fluid Mechanics, 2020
This paper presents a new efficient and robust numerical model for morphological flow simulation in river bends. The hydrodynamic model is developed by solving the two dimensional (2D) shallow water equations using a total variation diminishing (TVD ...
K. Bora, H. M. Kalita
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A TVD-WAF-based hybrid finite volume and finite difference scheme for nonlinearly dispersive wave equations

open access: yesWater Science and Engineering, 2015
A total variation diminishing-weighted average flux (TVD-WAF)-based hybrid numerical scheme for the enhanced version of nonlinearly dispersive Boussinesq-type equations was developed.
Jing Yin, Jia-wen Sun, Zi-feng Jiao
doaj   +1 more source

Numerical Simulation of Two Dimensional Unsteady Flow By Total Variation Diminishing Scheme

open access: yesInternational Journal Of Engineering & Applied Sciences, 2016
In recent years, many researchers have suggested various numerical techniques to solve the engineering problems like fluid flow intricacies. The objective of this paper is to introduce a numerical approach to simulate treatment of incompressible fluid flow in two-dimensional unsteady flow with the shallow water equations system. The governing equations
GHAREHBAGHI, Amin   +2 more
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Global smoothness preservation and the variation-diminishing property

open access: yes, 1999
In the center of our paper are two counterexamples showing the independence of the concepts of global smoothness preservation and variation diminution for sequences of approximation operators.
Gavrea Ioan   +4 more
core  

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