Results 71 to 80 of about 2,341,333 (275)

Three-dimensional response of double anchored sheet pile walls subjected to excavation and construction sequence

open access: yesHeliyon, 2019
In this study, a three-dimensional (3D) response of anchored sheet pile walls was investigated on double-anchored sheet pile system during soils excavation and tunnel construction sequence.
Massamba Fall   +2 more
doaj   +1 more source

Spectral analysis of random walk operators on euclidian space [PDF]

open access: yes, 2010
We study the operator associated to a random walk on $\R^d$ endowed with a probability measure. We give a precise description of the spectrum of the operator near $1$ and use it to estimate the total variation distance between the iterated kernel and its
Guillarmou, Colin, Michel, Laurent
core   +2 more sources

On Deterministically Approximating Total Variation Distance

open access: yes
Total variation distance (TV distance) is an important measure for the difference between two distributions. Recently, there has been progress in approximating the TV distance between product distributions: a deterministic algorithm for a restricted class of product distributions (Bhattacharyya, Gayen, Meel, Myrisiotis, Pavan and Vinodchandran 2023 ...
Feng, Weiming   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Accuracy of Approximation for Discrete Distributions

open access: yesJournal of Probability and Statistics, 2016
The paper is a contribution to the problem of estimating the deviation of two discrete probability distributions in terms of the supremum distance between their generating functions over the interval [0,1].
Tamás F. Móri
doaj   +1 more source

On Computing the Total Variation Distance of Hidden Markov Models

open access: yesCoRR, 2018
We prove results on the decidability and complexity of computing the total variation distance (equivalently, the $L_1$-distance) of hidden Markov models (equivalently, labelled Markov chains). This distance measures the difference between the distributions on words that two hidden Markov models induce.
openaire   +4 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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