Results 91 to 100 of about 8,284 (304)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Spectral characterization and Schrödinger operator of space-like submanifolds

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015
In this paper, we would like to study space-like submanifolds in a de Sitter spaces Spn+p(1). We define and discuss three Schrödinger operators LH, LR, LR/H and obtain some spectral characterizations of totally umbilical space-like submanifolds in terms ...
Shu Shichang, Zhu Tianmin
doaj   +1 more source

Radical Transversal Lightlike Submanifolds of Indefinite Para-Sasakian Manifolds

Demonstratio Mathematica, 2014
In this paper, we study radical transversal lightlike submanifolds and screen slant radical transversal lightlike submanifolds of indefinite para-Sasakian manifolds giving some non-trivial examples of these submanifolds.
Shukla S.S., Yadav Akhilesh
doaj   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Pseudo-Slant submaniolds of nearly δ- Lorentzian trans Sasakian manifolds [PDF]

Journal of Hyperstructures
Our focus is on the existence of certain structures and similarities between pseudo slant submanifolds and nearly δ- Lorentzian trans Sasakian manifolds.
Shamsur Rahman
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Pinching Results on Totally Real Submanifolds of a Locally Conformal Kähler Manifolds

Mathematics
This paper investigates the relationship between pseudo-umbilical and minimal totally real submanifolds in locally conformal Kähler space forms. Some rigidity theorems and an integral inequality are obtained using the moving-frame method and the DDVV ...
Noura M. Alhouiti, Ali H. Alkhaldi, Akram Ali, Piscoran Laurian-Ioan   +3 more
doaj   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

On Pseudo Cyclic Ricci Symmetric Manifolds

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2011
: The object of the present paper is to study concircularly symmetric (PCRS)n, concircularly recurrent (PCRS)n, decomposable (PCRS)n. Among others it is shown that in a decomposable (PCRS)n one of the decompositions is Ricci flat and the other ...
Shyamal Hui
doaj