Results 291 to 300 of about 2,065,152 (369)

Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening

open access: yesAdvanced Science, EarlyView.
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin   +6 more
wiley   +1 more source

Electronic Structure of Kramers Nodal‐Line Semimetal YAuGe and Anomalous Hall Effect Induced by Magnetic Rare‐Earth Substitution

open access: yesAdvanced Science, EarlyView.
The rare‐earth intermetallics YAuGe is identified as a Kramers nodal‐line semimetal, a topological state inherent to non‐centrosymmetric achiral lattices. Magnetic rare‐earth substitution induces an anomalous Hall effect, highlighting the impact of time‐reversal symmetry breaking on topological electronic states and offering insights into designing the
Takashi Kurumaji   +13 more
wiley   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu   +8 more
wiley   +1 more source

Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects

open access: yesAdvanced Science, EarlyView.
Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu   +13 more
wiley   +1 more source

Distributed Temporal Coding of Visual Memory Categories in Human Hippocampal Neurons Revealed by an Interpretable Decoding Model

open access: yesAdvanced Science, EarlyView.
This study examines how the human hippocampus encodes visual memory categories. By decoding spiking activity from CA3 and CA1 neurons using an interpretable model, it reveals that category‐specific representations emerge from distributed temporal coding.
Xiwei She   +17 more
wiley   +1 more source

Transforming the Poison Effects of Water Vapor into Benefits Over Adjustable Dual Acid Sites for Stable Plasma‐Catalysis

open access: yesAdvanced Science, EarlyView.
YxMnyOx+2y catalyst provides dual active sites of Lewis acid (Y3+) and Mn for the co‐adsorption of H2O and O3, and the fast dissociation of adsorbed H2O to surface *OH. Then, a newly OH‐accompanied pathway for O3 decomposition is formed, transforming H2O to active ·OH radical, with the assistance of high energy electrons in the plasma.
Si Chen   +7 more
wiley   +1 more source

No-touch versus conventional vein in coronary artery bypass grafting: three year follow-up of multicentre randomised PATENCY trial.

open access: yesBMJ
Tian M   +14 more
europepmc   +1 more source

A Full‐Range Proximity‐Tactile Sensor Based on Multimodal Perception Fusion for Minimally Invasive Surgical Robots

open access: yesAdvanced Science, EarlyView.
A full‐range proximity‐tactile sensing module is developed for safe operation of surgical robots, which performs multimodal fusion perception through ultrasonic sensor for long‐range proximity detection, capacitive sensor for close‐range proximity sensing, and triboelectric sensor for tactile sensing.
Dongsheng Li   +8 more
wiley   +1 more source

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