Results 51 to 60 of about 105,717 (288)

Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b [PDF]

open access: yesJournal of Neurophysiology, 2012
The molecular and physiological basis of the touch-unresponsive zebrafish mutant fakir has remained elusive. Here we report that the fakir phenotype is caused by a missense mutation in the gene encoding voltage-gated calcium channel 2.1b ( CACNA1Ab).
Low, Sean E   +5 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Procedure for the Determination of the Appropriate Protective Foil Size to Reduce Step Voltage Using a FEM Model and Evolutionary Methods

open access: yesApplied Sciences
When a fault occurs in a power transmission system, voltages that are dangerous to people may occur. The aim of this work is to present the following method of protection: the use of protective foil installed at the appropriate depth around the ...
Marko Jesenik   +3 more
doaj   +1 more source

Transparent switchboard [PDF]

open access: yes, 1973
A tin oxide coating is formed on a plate of glass and the coating is then etched away from the glass in thin lines to form separate electrical conductors which extend to one end of the plate and connect to either a vertical (column) or horizontal (row ...
Rasmussen, H. P.
core   +1 more source

Object-guided Spatial Attention in Touch: Holding the Same Object with Both Hands Delays Attentional Selection [PDF]

open access: yes, 2009
Previous research has shown that attention to a specific location on a uniform visual object spreads throughout the entire object. Here we demonstrate that, similar to the visual system, spatial attention in touch can be object guided.
Bettina Forster   +6 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Определение напряжения прикосновения на оборудовании подстанций с учетом статистического характера расчетов сопротивления грунта [PDF]

open access: yes, 2012
В работе предложен вероятностный подход к определению контактного напряжения с учетом статистического характера расчетов сопротивления почвы. Представлена методика оценки возможности появления значения контактного напряжения выше допустимой величины с ...
Колиушко, Георгий Михайлович   +2 more
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

ANALYSIS OF WIND TURBINE GROUNDING SYSTEMS IN TERMS OF TOUCH AND STEP VOLTAGES

open access: yesElectrica, 2019
Power generation from renewable resources is increasingly growing. The numbers of wind turbines and wind farms are increasing as well. Wind turbines and wind farms require grounding systems in order to protect the living creatures and turbine components ...
Çağrı KÖKSAL, Ömer GÜL
doaj   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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