Results 61 to 70 of about 191,063 (302)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Pieces of Iowa’s Past, February 15, 2012 [PDF]

open access: yes, 2012
Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government.

core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

INTERPRETASI EKOWISATA OLEH PEMANDU WISATA DI KAWASAN PARIWISATA UBUD

open access: yesSimbiosis: Journal of Biological Sciences
Tourism is one sector whose development which very intensively developed by the government. One form of sustainable tourism is ecotourism. Tour guides in ecotourism activities have an important role in connecting tourists with interpreted tourist ...
Ashira Istighfarah   +2 more
doaj   +1 more source

China Employment Law Update - August 2015 [PDF]

open access: yes, 2015
In This Issue: Government Announces Overtime Treatment for Special Holiday in September Significant Amendments Made to Shanghai Collective Contract Regulations MOHRSS Issues Draft Implementation Rules on Employment Contract Law Government Makes ...
Baker & McKenzie
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The impact of behaviors and skills of tour guides in guiding tourist groups. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
The aim of this study was to reveal the impact of the tour guide's behaviors and skills in guiding tourists groups in an efficient manner. To achieve the aim of the study, a random sample of (117) tour guides were selected and the descriptive approach ...
Dr. Mohammad Shabeb Kassawnh   +3 more
doaj  

Whale sharks of the western Caribbean: an overview of current research and cnservation efforts and future needs for effective management of the species [PDF]

open access: yes, 2007
Whale sharks (Rhincodon typus) are seasonal visitors to four sites in the Western Caribbean, 3 of which are encompassed by the Mesoamerican Barrier Reef.
Graham, Rachel T.
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The dynamic trio: The relationship between passion, perseverance and job satisfaction

open access: yesTourism
This work aims to enhance the understanding of the dynamic relationship between passion, perseverance and job satisfaction among tour guides, recognizing the interconnected nature of these elements and their impact on tourism experience.
Mitja Gorenak   +2 more
doaj   +1 more source

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