Results 141 to 150 of about 14,518 (290)

Multifactorial Machine Learning Algorithm Integration of Pain Mechanisms Can Predict the Efficacy of 3‐Week NSAID Plus Paracetamol in Patients With Painful Knee Osteoarthritis

open access: yesEuropean Journal of Pain, Volume 29, Issue 10, November 2025.
ABSTRACT Background Studies demonstrate that pain sensitization, epigenetic mechanisms, inflammation, and psychological factors might be predictive of treatment outcomes. Anti‐inflammatory therapy is recommended, but efficacy varies among patients. This study aimed to utilise machine learning to predict the analgesic responses of 3‐week NSAID plus ...
Rocco Giordano   +4 more
wiley   +1 more source

Effect of Pneumatic Tourniquet on Muscle Oxygen Tension [PDF]

open access: bronze, 1978
Seppo Santavirta   +2 more
openalex   +1 more source

Fatal drug overdoses in healthcare workers: A thematic framework analysis of coroner reports

open access: yesAddiction, Volume 120, Issue 11, Page 2270-2281, November 2025.
Abstract Background and aims Healthcare workers face specific vulnerabilities for drug overdose due to their unique access to medications, clinical knowledge and work‐related stress. This study aimed to understand the characteristics of fatal overdoses in healthcare workers with a view to providing guidance for preventative strategies.
Thikra Algahtani   +6 more
wiley   +1 more source

Timing of Tourniquet Removal after Knee Replacement [PDF]

open access: bronze, 1979
J H Newman, J. P. Jackson, W Waugh
openalex   +1 more source

Mixed Reality in Nursing Practice: A Mixed Methods Systematic Review

open access: yesJournal of Clinical Nursing, Volume 34, Issue 11, Page 4547-4559, November 2025.
ABSTRACT Aim(s) To review the current evidence on mixed reality (MR) applications in nursing practice, focusing on efficiency, ergonomics, satisfaction, competency, and team effectiveness. Design Mixed methods systematic review of empirical studies evaluating MR interventions in nursing practice.
Chandler H. Moser   +33 more
wiley   +1 more source

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang   +10 more
wiley   +1 more source

Evidence‐based standardized sample handling protocol for accurate blood‐based Alzheimer's disease biomarker measurement: Results and consensus of the Global Biomarker Standardization Consortium

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Blood‐based biomarkers (BBMs) have revolutionized Alzheimer's disease diagnosis and monitoring. Their pre‐analytical stability requires scrutiny. This study assessed pre‐analytical effects to inform a standardized sample handling protocol.
Inge M. W. Verberk   +19 more
wiley   +1 more source

Active Shooter Events: The Guardian Plan [PDF]

open access: yes, 2018
The decision on how to protect the children and youth while at schools is a serious conversation with varying agreements on the best practices. Some feel that school personnel should not be trained nor expected to be able to react to an armed person ...
Sampson, Pauline M., Walker, David R.
core   +1 more source

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