Results 91 to 100 of about 1,578,425 (314)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Toxic mechanism of cadmium exposure on cardiac tissue

open access: yes, 2000
The presence of toxic substances in the workplace environment requires systematic evaluation of exposure and health status in exposed subjects. Cadmium is a highly toxic element found in water.
Marques, S. F G   +5 more
core   +3 more sources

Analysis of Chemical Composition of Different Irreversible Hydrocolloids

open access: yesDentistry Journal, 2018
Irreversible hydrocolloids (IR) is a dental impression material commonly used in Brazilian and European dental practice because it is inexpensive, easy to handle, has good reproductive detail and is comfortable for the patient.
Antonio Ricardo Borges de Olival   +5 more
doaj   +1 more source

Toxic Substances Control Act, The

open access: yes, 1984
Title from PDF cover (viewed on Feb. 3, 2010).; "July 1984."; "EPA 560/1-83-002.

core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A perspective Study on Lead Poisoning: Exposure, Effects and Treatment

open access: yesInternational Journal of Economic and Environment Geology, 2019
Current studies focus on various aspects of lead ‘s poisoning, its distribution and interaction routes, adverse effects on human body and treatment procedures. Lead metal has been involved in human exercise from the past 6000 years.
Mishal Chaudhari, Shabbir Hussain, Hajira Rehman, Tanzeela Gulab Shahzady
doaj  

Identification of toxic and non-toxic Microcystis by three primers

open access: yes, 2004
To discriminate from toxic and non-toxic Microcystis, 3 pairs of primers epF/mb1R, mcF/teR and mcF/umR were designed, based on sequences of microcystin synthetase gene cluster.
Song Li-rong (lrsong@ihb.ac.cn)   +4 more
core  

Toxic Anterior Segment Syndrome After Phacoemulsification

open access: yes, 2013
Toxic anterior segment syndrome (TASS) caused by non-infectious agents is a sterile inflammation which occurs after anterior segment surgery and results in toxic damage to the intraocular tissues.
Gamze Dereli, Tamer Takmaz
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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