Results 81 to 90 of about 1,578,425 (314)
Toxic Algae Contamination and Demand for Shellfish: A Case Study of Demand for Mussels in Montreal [PDF]
Toxic algae blooms are a worldwide phenomena, which appear to be increasing in frequency and severity. These natural events cause product contaminations that often have significant economic consequences, including supply interruptions due to closed ...
Brooks, Priscilla M. +2 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Impact of Quasi-Regulatory Mechanisms on Polluting Behavior: Evidence from Pollution Prevention Programs and Toxic Releases [PDF]
To date, there is little convincing evidence on the effectiveness of “quasi-regulatory” mechanisms. Here I investigate how quasi-regulatory policies known as pollution prevention (“P2”) programs affect toxic pollution.
Linda Bui
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Quantum Dots in Therapeutic, Diagnostic and Drug Delivery Applications “A Brief Review”
Iranian Journal of Materials Science and Engineering, 2020 Synthesis of materials at nano scale is one of the main challenges in nanotechnology for different applications such as semiconductor, superconductors, electro-optics devices, advanced ceramics, refractories, diagnostic imaging and drug delivery ...
A. Nemati
doaj
Traumatic and Toxic Optic Neuropathies
, 2013 The clinical characteristics, pathogenesis, and treatment of traumatic and toxic neuropathies are given in this manuscript.
Huban Atilla
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Toxic exposure in America: estimating fetal and infant health outcomes [PDF]
We examine the effect of toxic exposure on U.S. infant and fetal mortality rates between 1989 and 2002 from toxic pollution released by facilities reporting to the Toxic Release Inventory (TRI).
Linda T.M. Bui +2 more
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source