Results 41 to 50 of about 941,918 (300)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2020 This chapter provides an overview of the international legal regime governing hazardous wastes (Basel Convention), toxic chemicals and pesticides (Rotterdam Convention), and persistent organic pollutants (Stockholm Convention) or the BRS legal regime in ...
Puthucherril, Tony George
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Ecological Impacts of Toxic Chemicals [PDF]
, 2011 Ecological Impacts of Toxic Chemicals presents a comprehensive, yet readable account of the known disturbances caused by all kinds of toxic chemicals on both aquatic and terrestrial ecosystems.
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Hazardous Household Substances: Alternatives That Are Relatively Free of Toxic Effects
EDIS, 2020 Some products that we use in our homes contain chemicals that are hazardous or toxic. We can reduce the potential for exposure to chemicals from household products and produce less hazardous household waste by using alternatives that are relatively free
Marie Hammer +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Global REACH?: The Potential International Impact of EU Chemicals Regulation [PDF]
, 2009 The central question of this paper is: Could the new EU chemicals regulation REACH play a role in international chemicals governance – and if so, how? The REACH Regulation is one of the largest and most controversial pieces of legislation that the EU ...
Katja Biedenkopf, Biedenkopf, Katja
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A review of the toxicity of chemical dispersants [PDF]
Reviews on Environmental Health, 2011 Chemical dispersants are a mixture of various surfactants and solvents. Most dispersants are proprietary, and the complete composition is not often public knowledge. Chemical dispersants used for the cleanup and containment of crude oil toxicity became a major concern after the 2010 Deepwater Horizon oil crisis in the Gulf of Mexico. During the crisis,
James, Wise, John Pierce, Wise
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Transference of occupational chemicals through breast milk [PDF]
, 2002 Plan BThe significance of this study stems from an interest in the information relating to the transference of occupational chemicals through breast milk as a job hazard for the Risk Control Specialist to consider. Three quarters of employed women are of
Levandoski, Karen A.
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