Results 11 to 20 of about 612,298 (206)

Fulvestrant-induced toxic epidermal necrolysis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
Toxic epidermal necrolysis is a condition with massive keratinocyte apoptosis, and it is associated with high mortality rates. Fulvestrant, an estrogen receptor antagonist, is indicated in the treatment of estrogen receptor-positive metastatic breast ...
Macarena Morales-Conde   +3 more
doaj   +2 more sources

Toxic epidermal necrolysis following a furosemide injection: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Toxic epidermal necrolysis is a life threatening adverse cutaneous reaction mostly following drug administration. It is characterized by extensive detachment of skin and mucous membranes with a more than 30% total body surface area involvement.
Clare Nakubulwa   +2 more
doaj   +2 more sources

Simvastatin-induced Toxic Epidermal Necrolysis

open access: yesJournal of Acute Disease, 2014
Toxic epidermal necrolysis comprises a severe immune-complex mediated hypersensitivity reaction that typically involves the skin and mucous membranes.
Emmanouil Petrou   +2 more
doaj   +2 more sources

Toxic Epidermal Necrolysis [PDF]

open access: yesJournal of Rawalpindi Medical College, 2020
Toxic epidermal necrolysis (TEN) is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and
Syed Naveed Ali Shah   +2 more
doaj   +2 more sources

Toxic epidermal necrolysis induced by lamotrigine treatment in a child [PDF]

open access: yesKorean Journal of Pediatrics, 2014
Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis.
Youngsuk Yi, Jeong Ho Lee, Eun Sook Suh
doaj   +3 more sources

A case series of allopurinol-induced toxic epidermal necrolysis

open access: yesIndian Journal of Dermatology, 2011
This is a case series of allopurinol-induced toxic epidermal necrolysis. Revisiting the indications of using allopurinol in asymptomatic hyperuricemia and a critical reappraisal of the safety profile of allopurinol is done in this article.
Harneet Ranu   +2 more
doaj   +2 more sources

Cutaneous approach in toxic epidermal necrolysis [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2017
INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality.
Francisco Carlos Santos Neto   +6 more
doaj   +3 more sources

Skin Detachment and Regrowth in Toxic Epidermal Necrolysis [PDF]

open access: yesCase Reports in Dermatology, 2010
Toxic epidermal necrolysis is a rare but clinically well-described dermatological pathology. However, clinical pictures of this disorder in text books do not reflect its dynamic evolution.
Laurence Feldmeyer   +4 more
doaj   +2 more sources

Toxic epidermal necrolysis [PDF]

open access: yesJournal of the American Academy of Dermatology, 2007
Toxic epidermal necrolysis (TEN) is an unpredictable, life-threatening drug reaction associated with a 30% mortality. Massive keratinocyte apoptosis is the hallmark of TEN. Cytotoxic T lymphocytes appear to be the main effector cells and there is experimental evidence for involvement of both the Fas-Fas ligand and perforin/granzyme pathways.
Frederick A, Pereira   +2 more
  +7 more sources

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

open access: yesMedisur
Stevens-Johnson syndrome and toxic epidermal necrolysis are severe mucocutaneous rare diseases with high morbid mortality characterized by generalized epidermal necrosis and skin detachment; They are distinguished from each other due to the extent of ...
Jeanneth Elizabeth Jami Carrera   +3 more
doaj   +1 more source

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