Results 21 to 30 of about 9,182 (184)
Carbamazepine-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap With Severe Ocular and Oral Involvement: A Pediatric Case Report From Uganda. [PDF]
ABSTRACT We report a case of carbamazepine‐induced Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) overlap in an 11‐year‐old Ugandan boy who presented with fever, facial swelling, ocular redness with photophobia, painful oral ulceration, and widespread epidermal detachment involving more than 10% of the body surface area.
Sandeyl AA +5 more
europepmc +2 more sources
Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový +8 more
doaj +1 more source
Identifying the incidence of rash, Stevens-Johnson syndrome and toxic epidermal necrolysis in patients taking lamotrigine: a systematic review of 122 randomized controlled trials [PDF]
Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic
Romi Bloom, Kyle T. Amber
doaj +2 more sources
Toxic epidermal necrolysis (TEN) is a life-threatening condition in which the epidermis blisters and peels in large sheets. The clinical syndrome and diagnosis are reviewed. Current treatment and prevention of complications are discussed. The key to low morbidity and mortality in TEN is early intervention.
Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA ( host institution ) +4 more
openaire +5 more sources
Fulvestrant-induced toxic epidermal necrolysis [PDF]
Toxic epidermal necrolysis is a condition with massive keratinocyte apoptosis, and it is associated with high mortality rates. Fulvestrant, an estrogen receptor antagonist, is indicated in the treatment of estrogen receptor-positive metastatic breast ...
Macarena Morales-Conde +3 more
doaj +1 more source
Ceftriaxone-induced toxic epidermal necrolysis mimicking burn injury: a case report
Introduction Toxic epidermal necrolysis is a rare exfoliative disorder with a high mortality rate. Case presentation We present a 70-year-old woman of Iranian descent who presented with toxic epidermal necrolysis that was initially diagnosed as a scald ...
Billig Allan, Cohen Sarit, Ad-El Dean
doaj +1 more source
The authors present three cases diagnosed as toxic epidermal necrolysis and discuss the early use of steroid therapy in the treatment of this disease.
Burhan Say, Erdoğan Usubütün
doaj +1 more source
Toxic epidermal necrolysis is a life-threatening dermatological emergency with high mortality if not treated in time. Here we report a case of toxic epidermal necrolysis due to carbamazepine in rural Nepal in COVID-19 pandemic who was successfully ...
Vikash Paudel, Deepa Chudal
doaj +1 more source
Simvastatin-induced Toxic Epidermal Necrolysis
Toxic epidermal necrolysis comprises a severe immune-complex mediated hypersensitivity reaction that typically involves the skin and mucous membranes.
Emmanouil Petrou +2 more
doaj +1 more source
Toxic epidermal necrosis associated with afatinib: A case report and literature review
ObjectiveTo report a case of afatinib-induced toxic epidermal necrosis (TEN), in a patient with metastatic non-small cell lung cancer (NSCLC) and compare these findings with that of evaluate similarities and differences to other cases reported in the ...
Wei Yang, Yansong Lu, Ze Wu, Jun Niu
doaj +1 more source

