Results 51 to 60 of about 9,182 (184)

Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis, A Review of Pathogenesis, Clinical Features, Diagnosis and Treatment

Journal of Education, Health and Sport, 2022
Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, acute conditions, potentially life-threatening, immune-mediated and often unpredictable.
Martyna Rozenbajgier, Justyna Wójcik-Grudzień, Paulina Pawłowska, Alicja Ozga-Stachurska   +3 more
doaj   +1 more source

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Important Points in Toxic Epidermal Necrolysis Management

Oman Medical Journal, 2019
There are several important points that the authors did not highlight which are critical and form the cornerstones in the care of patients with possible TEN.
Sultan
doaj   +1 more source

The Accuracy of Frozen Section Histopathology in the Rapid Diagnosis of Severe Cutaneous Adverse Reactions: A Systematic Review and Meta‐Analysis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Frozen section analysis enables rapid diagnosis, but its diagnostic accuracy in the setting of severe cutaneous adverse reactions (SCARs) remains poorly defined. Methods A systematic review and meta‐analysis were performed to evaluate the diagnostic performance of frozen sections in the rapid identification of SCARs, with a focus on
Cody C. Frear, Louise Frear, Duncan Lambie, Amanda Godbolt   +3 more
wiley   +1 more source

Toxic epidermal necrolysis in a 5-year-old boy - case report

Brazilian Dental Science, 2016
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are considered a spectrum of acute life-threatening mucocutaneous reaction that differ only in severity, often induced by drugs.
Pavan Puri, Sana Shaikh, Adesh Kakade, Rajiv Desai, Rahul Rahinj, Pankaj Shirsat   +5 more
doaj   +1 more source

Cutaneous approach in toxic epidermal necrolysis [PDF]

Revista Brasileira de Cirurgia Plástica, 2017
INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality.
Francisco Carlos Santos Neto, Pedro Salomão Piccinini, Jean Miguel Andary, Lucas Dal Pozzo Sartori, Lucas Tomkowski Cancian, Carlos Oscar Uebel, Milton Paulo de Oliveira   +6 more
doaj   +1 more source

Effect and length of doxycycline administration in elderly patients with bullous pemphigoid

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease and primarily affects the elderly. Systemic corticosteroids and immunosuppressive drugs are the standard treatment, but side effects often restrict their use. Doxycycline has been proposed as an alternative, but there is limited long‐term, real‐world data on its
Alena Merkel‐Ropele, Wolfgang Salmhofer, Peter Wolf   +2 more
wiley   +1 more source

Toxic Epidermal Necrolysis Associated with Misoprostol: A Case Report

International Medical Case Reports Journal, 2023
Okbu Frezgi,1 Mulugeta Russom2– 4 1Gynecology and Obstetric Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea; 2Eritrean Pharmacovigilance Centre, National Medicines and Food Administration, Ministry of Health, Asmara, Eritrea ...
Frezgi O, Russom M
doaj  

Toxic Epidermal Necrolysis in an Irradiated Patient Treated with a Nanocrystalline Silver Dressing

Case Reports in Dermatology, 2012
Toxic epidermal necrolysis syndrome is a severe exfoliative condition, which may be triggered by anticonvulsant medication. We report a case of toxic epidermal necrolysis syndrome in a 43-year-old female who was receiving radiotherapy for brain ...
Tamara Z. Vern-Gross, Areta Kowal-Vern, Stathis J. Poulakidas   +2 more
doaj   +1 more source

A guide to laser microdissection‐based proteomics

The FEBS Journal, EarlyView.
This review takes researchers through the full laser microdissection proteomics workflow—from tissue preparation and image analysis to sample processing and mass spectrometry—offering practical solutions to common challenges at each step. Real‐world examples from across the field illustrate how the technology is being applied to disease tissue, making ...
Cheng Shen, Kael Schoffer, Charlotte Williams, Maria C. Tanzer   +3 more
wiley   +1 more source