Results 71 to 80 of about 9,182 (184)

Integrating Pharmacogenomic Testing Within the 4Ms Framework for Management of Behavioral Symptoms in Advanced Vascular Dementia: A Case Study

open access: yesJournal of the American Geriatrics Society, EarlyView.
Pharmacogenomic‐guided managment of behavioral symptoms within the 4Ms framework.
Gianna Franco   +3 more
wiley   +1 more source

Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report

open access: yesJournal of Nepal Medical Association, 2019
Toxic epidermal necrolysis is a potentially life threatening dermatologic disorder characterized by widespread erythema, necrosis and bullas, detachment of epidermis and mucous membrane resulting in exfoliation, possible sepsis and even death.
Vidya Mahto   +2 more
doaj   +1 more source

Resolution of Paediatric Cow's Milk Allergy Is Associated With Low Tfh Cell Frequencies and Elevated IL‐17 and IL‐22 Levels

open access: yes
Clinical &Experimental Allergy, EarlyView.
Guillaume Lezmi   +7 more
wiley   +1 more source

Systemic Therapy for Paediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review of Current Evidence and Limitations

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The role of systemic therapy in paediatric Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) remains undefined. Management is primarily guided by observational data and variable practice patterns. This systematic review aims to integrate recent evidence and evaluate clinical outcomes associated with systemic therapies in ...
Samantha Ting   +3 more
wiley   +1 more source

Epidermal necrolysis (Stevens–Johnson syndrome and toxic epidermal necrolysis): Historical considerations

open access: yesDermatologica Sinica, 2013
Objective: To describe the history of toxic epidermal necrolysis, before and after the original report by the British dermatologist Alan Lyell in 1956. Methods: Subjective expert choice of key advances in the comprehension of the nosology, classification,
Jean-Claude Roujeau
doaj   +1 more source

Development of Multidisciplinary Consensus‐Informed Guidance for the Management of Paediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Among Clinicians From Australasian Tertiary Referral Hospitals

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Paediatric Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe mucocutaneous reaction requiring coordinated multidisciplinary care. Existing guidelines provide evidence‐based recommendations, but implementation across tertiary paediatric hospitals requires practical consensus on local resources.
Patrick David Mahar   +32 more
wiley   +1 more source

TOXIC EPIDERMAL NECROLYSIS (LYELL’S SYNDROME)

open access: yesЖурнал инфектологии, 2018
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E. N. Kudelka   +6 more
doaj   +1 more source

Putative cutaneous adverse drug reactions in two dogs

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary We describe two cases of cutaneous adverse drug reactions (CADR) in dogs. Case 1 presented with erythematous macules with sharply demarcated margins on the abdomen and inguinal area and depigmentation on the lip. Skin lesions appeared after 3 weeks of administration of anti‐epileptic drugs, including phenobarbital.
Je‐Seong Kwon   +4 more
wiley   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow   +14 more
wiley   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier   +37 more
wiley   +1 more source

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