Results 71 to 80 of about 483,640 (182)

Treatment Outcomes of Hospitalized Patients With Inflammatory Bowel Disease at a Tertiary Care Center in Nepal: A Cross‐Sectional Study

JCC Plus, Volume 1, Issue 4, July 2026.
Overall, patients with IBD constituted 1.6% (n = 37) of all admissions to the gastroenterology ward for any indication. Most (2/3rd) hospitalized patients with IBD responded to conventional therapy; one third required advanced therapy or surgery. In‐hospital mortality was high at 5%, probably related to delayed diagnosis, limited access to advanced ...
Ajay Kumar Yadav, Bhupendra Kumar Basnet, Ramila Shrestha, Ajit Khanal, Milan Shrestha, Mukesh Sharma Poudel   +5 more
wiley   +1 more source

Toxic Megacolon – the Complication of an Infection with Clostridium difficile after an Odontogenic Abscess. Case Presentation

Journal of Interdisciplinary Medicine, 2019
Background:Clostridium difficile (CD) is the major cause of nosocomial antibiotic-associated infections, having as main manifestation diarrhea and life-threatening inflammation of the colon.
Suciu Nicolae, Benedek Zalán, Sorlea Sorin, Coroș Marius Florin   +3 more
doaj   +1 more source

Inflammatory Bowel Diseases: the Surgical Perspective [PDF]

Modern Medicine, 2019
Inflammatory bowel diseases (IBD), namely Crohn’s disease and ulcerative colitis, are relatively rare diseases in our country, known as a low prevalence geographic region.
SOCEA Bogdan, DUMITRESCU Dan, BRATU Ovidiu Gabriel , CARAP Alexandru Constantin, BADIU Dumitru Cristinel, BOLOCAN Alexandra, PADURARU Dan Nicolae, MISCHIANU Dan, CONSTANTIN Vlad Denis   +8 more
doaj   +1 more source

Long‐term outcomes of children with ulcerative colitis after acute severe colitis: A GETAID pédiatrique multicenter study

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 1, Page 117-126, July 2026.
Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet, Agathe Beauvais, Frank Ruemmele, Raphael Enaud, Thierry Lamireau, Rémi Duclaux‐Loras, Claire Dupont, Stéphanie Willot, Laure Bridoux‐Henno, Georges Dimitrov, Julie Lemale, Vincent Guinard‐Samuel, Valérie Bertrand, Anne Breton, Christine Martinez Vinson, Stéphanie Coopman, Delphine Ley, Bénédicte Pigneur, and the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du tube Digestif (GETAID) pédiatrique   +18 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

A young leukemic patient with unusual catastrophic intestinal complication

Indian Journal of Pathology and Microbiology, 2015
A 14-year-old child with acute lymphoblastic leukemia who had completed induction chemotherapy presented with fever and diffuse musculoskeletal pains which was thought to be a constellation of myositis, arthralgias and arthritis.
Kim Vaiphei, Amita Trehan, Man Updesh Singh Sachdeva, Pankaj Malhotra   +3 more
doaj   +1 more source

A Case of Fulminant Immune‐Related Enterocolitis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Combination therapy with immune checkpoint inhibitors (ICIs) has become a standard treatment for metastatic renal cell carcinoma (mRCC). However, ICIs may also cause immune‐related adverse events. We report a case of mRCC that developed fulminant immune‐related enterocolitis.
Kasumi Kanai, Takayuki Sumiyoshi, Hiroki Kitamoto, Yuki Teramoto, Yuta Mine, Jin Kono, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi   +9 more
wiley   +1 more source

Pseudomembranous colitis and toxic megacolon due to C. difficile in an inpatient hospitalized for home accident

Clinical Management Issues, 2015
Clostridium difficile infection (CDI) is the main cause of hospital-acquired diarrhea. It can result in symptoms ranging from moderate diarrhea to pseudomembranous colitis.
Piergiorgio Chiriacò
doaj   +1 more source

FROG (Frequency Rates, mOrbidities and timinGs) of Surgical Interventions for UC: A Protocol for an International, Multi‐Centre, Retrospective Cohort Study on Frequency Rates, Morbidities and Timings of Surgical Interventions for Ulcerative Colitis

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background The surgical journey of patients diagnosed with ulcerative colitis (UC) typically begins with an index colectomy, which may be followed by restorative procedures or further operations due to complications. Variation in surgical strategies exists, impacting patient outcomes.
Orestis Argyriou, Itai Ghersin, Guy Worley, Phil Tozer, Ailsa Hart, Kapil Sahnan   +5 more
wiley   +1 more source

Clostridioides difficile infection leading to fulminant colitis with toxic megacolon

Autopsy and Case Reports, 2023
Clostridioides difficile infection (CDI) is the culprit of millions of nosocomial infections in the United States. Programs that successfully decrease its incidence, therefore, render cost savings for the healthcare system.
Fareed Rajack, Shawn Medford, Tammey Naab   +2 more
doaj