Toxic Megacolon and Acute Ischemia of the Colon due to Sigmoid Stenosis Related to Diverticulitis
We present a rare case of toxic megacolon accompanied by necrosis of the colon due to chronic dilation caused by stenosis of the sigmoid colon as a complication of diverticulitis.
P. Antonopoulos +5 more
doaj +1 more source
Imaging of ischemia, obstruction and infection in the abdomen [PDF]
Intestinal ischemia is a serious condition that continues to be associated with mortalities in excess of 70%. Intestinal obstruction and gastrointestinal tract sepsis are common conditions, accounting for a large proportion of patients admitted to ...
Maher, Michael M. +4 more
core +1 more source
Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]
The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R +6 more
core +1 more source
Outcome of Toxic Megacolon during Pregnancy
Two patients with ulcerative colitis required subtotal colectomy and ileostomy for toxic megacolon during pregnancy. Subsequently, a mucosal proctectomy with ileal pouch-anal anastomosis was performed. These two patients who avoided permanent ileostomies
Carl Chartrand-Lefebvre +4 more
doaj +1 more source
Toxic megacolon is a severe complication of Clostridium difficile infection (CDI) with a high percentage of mortality. The mainstay of treatment is currently represented by medical management, while surgical intervention is indicated in patients not ...
Addolorata Masiello +5 more
doaj +1 more source
Liver Transplantation for Polycystic Liver Disease [PDF]
Four female patients with severe complications of polycystic liver disease were treated with liver replacement; two patients were also given kidneys from their liver donors. All four of the patients were suffering from extreme fatigue.
Gordon, R +5 more
core +1 more source
A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian +12 more
core +2 more sources
Severe Clostridium difficile infections in intensive care units: Diverse clinical presentations
Background: Clostridium difficile infections (CDIs) cause significant mortality and morbidity. Critically ill patients are susceptible to CDIs and tend to have severe CDIs, and their clinical presentations are not merely diarrhea.
Jen-Chieh Lee +4 more
doaj +1 more source
The role of colonoscopy in the management of intestinal obstruction: a 20-year retrospective study [PDF]
Purpose The aim of the study was to assess the use colonoscopy over time in the assessment of large bowel obstruction in a tertiary university hospital.
Konstantinos H Katsanos +6 more
core +1 more source
Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M +8 more
core +2 more sources

