Results 41 to 50 of about 3,999 (210)

Blowhole Colostomy for Clostridium difficile-Associated Toxic Megacolon

Case Reports in Surgery, 2016
We present the case of a 58-year-old man who underwent urgent blowhole colostomy for toxic megacolon (TM) secondary to Clostridium difficile infection (CDI).
Jeroen Kerstens, Ian Diebels, Charles de Gheldere, Patrick Vanclooster   +3 more
doaj   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Nasogastric Delivery of Fecal Microbiota Transplantation for the Treatment of Fulminant Clostridioides difficile Infection: A Case Report

JGH Open
Introduction Clostridioides difficile infection (CDI) is a significant cause of antibiotic‐associated diarrhea with high morbidity and mortality, particularly in cases of fulminant disease. Fecal microbiota transplantation (FMT) has demonstrated efficacy
Amitjeet Singh, Edward Young, Aashish Maurya, Arvind Rajagopalan   +3 more
doaj   +1 more source

A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation

Gut and Liver, 2015
Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%.
doaj   +1 more source

Toxic Megacolon: Background, Pathophysiology, Management Challenges and Solutions [Corrigendum]

Clinical and Experimental Gastroenterology, 2021
Desai J, Elnaggar M, Hanfy AA, Doshi R. Clin Exp Gastroenterol. 2020;13:203—210. The authors wish to add the following reference to the end of the reference section on page 210. 60. UpToDate Inc. Toxic megacolon. Alphen aan den Rijn: Wolters Kluwer;
Desai J, Elnaggar M, Hanfy AA, Doshi R
doaj  

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model [PDF]

, 2018
Indexación: Scopus.Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic
Ababouch, Abt, Ananthakrishnan, Barbour, Bartolotta, Bergsson, Bhattacharjee, Buckley, Burke, Carpo, Chen, Clark, Croasdell, Crowther, Dapa, Dapa, Dayrit, de Roos, Deakin, Deng, Desai, Edwards, Ekanayaka, Eyres, Ferreyra, Fischer, Francis, Galbraith, German, Harnvoravongchai, Hinton, Huang, Hung, Hung, Immanuel, Johnson, Kabara, Katan, Kim, Kint, Kitahara, Kliewer, Liu, Louie, Lynch, Martin, Martin, May, McDonald, McEllistrem, Miller, Nakatsuji, Namkung, Nobmann, Pettit, Pizarro-Guajardo, Pruitt, Rodriguez-Palacios, Rouse, Ruhr, Ruzin, Shearer, Shilling, Smits, Sorg, Surawicz, Theinsathid, Thompson, Vardakas, Villafuerte Galvez, Wilcox, Yonezawa   +71 more
core   +1 more source

A Case of Fulminant Immune‐Related Enterocolitis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Combination therapy with immune checkpoint inhibitors (ICIs) has become a standard treatment for metastatic renal cell carcinoma (mRCC). However, ICIs may also cause immune‐related adverse events. We report a case of mRCC that developed fulminant immune‐related enterocolitis.
Kasumi Kanai, Takayuki Sumiyoshi, Hiroki Kitamoto, Yuki Teramoto, Yuta Mine, Jin Kono, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi   +9 more
wiley   +1 more source

043. Multidiciplinary Management of Toxic Megacolon in Ulcerative Colitis: A Case Report and Review of Current Practice

JBN (Jurnal Bedah Nasional)
Background: Toxic megacolon is a life-threatening condition characterized by extreme colonic dilation and systemic toxicity. It often results from underlying inflammatory bowel disease, such as ulcerative colitis, or infectious colitis. Early recognition
Ridho Kurnianda, Rini Suswita, Yessy Setiawati   +2 more
doaj   +1 more source

Management of Severe Attacks of Ulcerative Colitis with New Technologies

Canadian Journal of Gastroenterology, 1990
Barium enema and colonoscopy are contraindicated in severe attacks of ulcerative colitis because of the possibility of toxic megacolon and perforation.
M Campieri, P Gionchetti, A Belluzzi, M Tampieri, C Brignola, E Bertinelli, V Arienti, P Iannone, M Miglioli, L Barbara   +9 more
doaj   +1 more source

FROG (Frequency Rates, mOrbidities and timinGs) of Surgical Interventions for UC: A Protocol for an International, Multi‐Centre, Retrospective Cohort Study on Frequency Rates, Morbidities and Timings of Surgical Interventions for Ulcerative Colitis

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background The surgical journey of patients diagnosed with ulcerative colitis (UC) typically begins with an index colectomy, which may be followed by restorative procedures or further operations due to complications. Variation in surgical strategies exists, impacting patient outcomes.
Orestis Argyriou, Itai Ghersin, Guy Worley, Phil Tozer, Ailsa Hart, Kapil Sahnan   +5 more
wiley   +1 more source